Purpose To investigate the role of T-cell-mediated immune response in a monophasic
experimental autoimmune uveitis (EAU). Methods A monophasic EAU was induced in Lewis …

Purpose.: Both Th17 and Th1 cells contribute to experimental autoimmune uveoretinitis
(EAU). Interleukin-6 (IL-6) blockade inhibits Th17 differentiation in EAU and potently …

Immunopathogenic roles for both Th1 (CD4+ IFN‐γ+) and Th17 (CD4+ IL‐17A+) cells have
been demonstrated in experimental autoimmune uveitis (EAU). However, the role for …

The aim of this study is to explore the dynamic changes in IL-17-expressing T cells
(Th17)/Treg expression in monophasic experimental autoimmune uveitis (mEAU). mEAU …

Abstract IL-17-producing CD4+ T cells, so called Th17 cells, constitute a newly identified
inflammatogenic cell population, which is critically involved in some inflammatory diseases …

Experimental autoimmune uveitis (EAU) represents autoimmune uveitis in humans. We
examined the role of the interleukin (IL)-23–IL-17 and IL-12–T helper cell (Th) 1 pathways in …

Objective To assess the regulation of antigen specific Th17 cells differentiation in
experimental autoimmune uveitis (EAU). Methods A randomized controlled trials research …

Abstract Purpose Regulatory T cells (Tregs) have been intensively studied in a myriad of
autoimmune diseases. As for noninfectious uveitis (NIU), results have been contradictory …

In the current study, we showed that in vivo administration of an anti-CD25 Ab (PC61)
decreased the Th17 response in C57BL/6 mice immunized with the uveitogenic peptide …

Objective: Experimental autoimmune uveitis (EAU) represents autoimmune uveitis in
humans, among which B10. RIII and C57BL/6 are the frequently used strains in mice, but to …