Recent reports make use of the zebrafish to study complex behavior such as addiction,
anxiety, or learning and memory. We have established reliable tests and appropriate …

Mounting evidence implicates the zebrafish (Danio rerio) as a promising model species for
reward and addiction research. Modeling drug abuse-related behavior in both adult and …

Background Addiction is a pathological dysregulation of the brain's reward systems,
determined by several complex genetic pathways. The conditioned place preference test …

Addiction is a complex psychiatric disorder considered to be a disease of the brain's natural
reward reinforcement system. Repeated stimulation of thereward'pathway leads to adaptive …

Understanding the molecular basis of addiction could be greatly aided by using forward
genetic manipulation to lengthen the list of candidate genes involved in this complex …

Drug abuse and dependence are multifaceted disorders with complex genetic
underpinnings. Identifying specific genetic correlates is challenging and may be more …

Continued usage of cocaine is determined by genetic, conditioned and homeostatic factors,
while it is reinforced by drug-induced reward and the emotionally negative state of drug …

Zebra fish may be an ideal vertebrate model system for numerous human diseases with
which the genetics and biological mechanisms of the disease may be studied. Zebra fish …

The zebrafish (Danio rerio) has become an excellent tool to study mental health disorders,
due to its physiological and genetic similarity to humans, ease of genetic manipulation, and …

Both natural rewards and addictive substances have the ability to reinforce behaviors. It has
been unclear whether identical neural pathways mediate the actions of both. In addition …