Marfan syndrome (MFS), a multisystemic connective disorder, caused by fibrillin 1 gene
mutations with autosomal dominant inheritance. The disease spectrum is wide and the …

Marfan syndrome is an autosomal dominant connective tissue disease with an estimated
incidence of 1 in 5000 individuals. In 90% of cases it is caused by mutations in the gene for …

Marfan syndrome is an autosomal dominant connective tissue disease with an estimated
incidence of 1 in 5000 individuals. In 90% of cases it is caused by mutations in the gene for …

Marfan syndrome (MFS) is a relatively rare disease of the connective tissue that affects
several organs of the body. Cardiovascular abnormalities such as aortic root dilatation and …

Marfan syndrome (MFS), a relatively common autosomal dominant hereditary disorder of
connective tissue with prominent manifestations in the skeletal, ocular, and cardiovascular …

Marfan's syndrome was once a disease of unknown cause, and those affected often died
young from aortic dissection. Today, most patients with Marfan's syndrome who receive …

Marfan syndrome (MFS) is an autosomal dominant genetic disorder caused by mutations in
the fibrillin-1 gene. Acute aortic dissection is the leading cause of death in patients suffering …

Marfan syndrome (MFS) is a connective tissue disease inherited in an autosomal dominant
fashion and associated with a decreased life expectancy. Skeletal features as well as a …

Marfan syndrome is an autosomal dominant disorder of the connective tissues, with mutation
on the fibrillin-1 gene encoding for fibrillin, a major component of the extracellular …

Background Marfan syndrome (MFS) is a disorder of autosomal dominant inheritance, in
which aortic root dilation is the main cause of morbidity and mortality. Fibrillin-1 (FBN-1) …