Marfan syndrome is an autosomal dominant disorder of connective tissue with an incidence
of approximately 1 in 20 000 (1). The disorder is characterized by clinical manifestations in …

Abstract Background/Methods. Marfan syndrome (MFS) is a heritable connective tissue
disorder usually caused by a mutation in the fibrillin 1 (FBN1) gene. Typical characteristics of …

Background—It has been shown that losartan reduces aortic dilatation in patients with
Marfan syndrome. However, treatment response is highly variable. This study investigates …

Marfan syndrome (MFS) is an autosomal dominant heritable disorder of connective tissue
that affects the cardiovascular, skeletal, ocular, pulmonary, and nervous systems and is …

Background and Objectives Marfan syndrome (MFS) is a connective tissue disorder with
autosomal dominant inheritance and a highly variable clinical spectrum. However, there are …

Marfan syndrome (MFS) is an autosomal dominant disorder of the body's connective tissue,
caused by mutations in the fibrillin-1 (FBN1) gene. The estimated prevalence of the …

Abstract Marfan Syndrome (MfS) is an autosomal dominant inherited connective tissue
disorder with variable phenotypic expression of cardiovascular, skeletal and ocular …

Marfan syndrome (MFS) is an autosomal dominant inherited disease of the connective
tissue with multiorgan involvement (skeleton, cardiovascular, eyes, skin, lungs) …

The Marfan syndrome is an autosomal dominant disorder of the connective tissue with
mutations on the fibrillin-1 gene encoding for fibrillin, a major component of the extracellular …

Marfan syndrome is a heritable disorder of the connective tissue with an estimated
prevalence of 1 in 5000 individuals and no predilection for either sex. The syndrome is …