Melatonin is a neurohormone synthesized in the pineal gland during the dark period in all
species, including humans. The diversity and differences in melatonin receptor distribution …

Highlights•Pathways controlling melatonin secretion are complex.•There are various causes
of melatonin disturbance.•Evaluation of melatonin secretion clinically requires long time …

Melatonin is a lipophilic hormone, mainly produced and secreted at night by the pineal
gland. Melatonin synthesis is under the control of postganglionic sympathetic fibers that …

Melatonin is a hormone produced mainly by the pineal gland in most vertebrate species,
including humans. Recent metabolic, receptor and functional studies created a picture of the …

Melatonin is an evolutionarily conserved molecule that serves a time-keeping function in
various species. In vertebrates, melatonin is produced predominantly by the pineal gland …

Melatonin, a hormone produced primarily by the pineal gland, is also secreted from the gut
and eye during darkness. There are three classes of melatonin receptors, MT< sub> 1, MT< …

Melatonin, dubbed the hormone of darkness, is known to regulate a wide variety of
physiological processes in mammals. This review describes well-defined functional …

The goal of the article is to provide a clearer understanding of how melatonin and its related
analogs interact with melatonin receptors with the hope of developing important tools and …

Melatonin is a fascinating molecule that has captured the imagination of many scientists
since its discovery in 1958. In recent times, the focus has changed from investigating its …

The functional versatility and diversity of melatonin has exceeded everyone's expectations.
The evidence is substantial that melatonin has multiple receptor-mediated and receptor …