Detrimental impact of the IL-33/ST2 axis in an animal infection model with Cryptococcus neoformans
K Ueno, Y Miyazaki - Allergology International, 2023 - jstage.jst.go.jp
abstract Cryptococcus neoformans and Cryptococcus gattii are pathogenic fungi that infect
the human respiratory system and cause life-threatening pulmonary cryptococcosis. The …
the human respiratory system and cause life-threatening pulmonary cryptococcosis. The …
IL-33 signaling regulates innate and adaptive immunity to Cryptococcus neoformans
A Flaczyk, CU Duerr, M Shourian, EI Lafferty… - The Journal of …, 2013 - journals.aai.org
Susceptibility to progressive infection with the fungus Cryptococcus neoformans is
associated with an allergic pattern of lung inflammation, yet the factors that govern this host …
associated with an allergic pattern of lung inflammation, yet the factors that govern this host …
Lung epithelium is the major source of IL-33 and is regulated by IL-33-dependent and IL-33-independent mechanisms in pulmonary cryptococcosis
L Heyen, U Müller, S Siegemund… - FEMS Pathogens …, 2016 - academic.oup.com
Inhalation of the fungus Cryptococcus neoformans (C. Â neoformans) results in pulmonary
cryptococcosis associated with IL-33-dependent type 2 immunity. Lung epithelium …
cryptococcosis associated with IL-33-dependent type 2 immunity. Lung epithelium …
A comparative study of IL-33 and its receptor ST2 in a C57BL/6 J mouse model of pulmonary Cryptococcus neoformans infection
Z Wang, Q Ma, J Jiang, X Yang, E Zhang, Y Tao… - Medical Microbiology …, 2023 - Springer
It has been reported that IL-33 receptor ST2 deficiency mitigates Cryptococcus neoformans
(C. neoformans) pulmonary infection in BALB/c mice. IL-33 may modulate immune …
(C. neoformans) pulmonary infection in BALB/c mice. IL-33 may modulate immune …
[HTML][HTML] IL-23 dampens the allergic response to Cryptococcus neoformans through IL-17–independent and–dependent mechanisms
WA Szymczak, RS Sellers, L Pirofski - The American journal of pathology, 2012 - Elsevier
The cytokines IL-23 and IL-17 have been implicated in resistance to cryptococcal disease,
but it is not clear whether IL-23–mediated production of IL-17 promotes fungal containment …
but it is not clear whether IL-23–mediated production of IL-17 promotes fungal containment …
[HTML][HTML] T1/ST2 promotes T helper 2 cell activation and polyfunctionality in bronchopulmonary mycosis
D Piehler, A Grahnert, M Eschke, T Richter, G Köhler… - Mucosal …, 2013 - Elsevier
Abstract Interleukin (IL)-33 enhances T helper (Th) 2 immunity via its receptor T1/ST2.
Infection with the yeast-like pathogen Cryptococcus neoformans is usually controlled by a …
Infection with the yeast-like pathogen Cryptococcus neoformans is usually controlled by a …
IL-13 induces disease-promoting type 2 cytokines, alternatively activated macrophages and allergic inflammation during pulmonary infection of mice with …
U Muller, W Stenzel, G Köhler, C Werner… - The Journal of …, 2007 - journals.aai.org
In the murine model of Cryptococcus neoformans infection Th1 (IL-12/IFN-γ) and Th17 (IL-
23/IL-17) responses are associated with protection, whereas an IL-4-dependent Th2 …
23/IL-17) responses are associated with protection, whereas an IL-4-dependent Th2 …
Effects of combination of Cryptococcus gattii and IFN-γ, IL-4 or IL-27 on human bronchial epithelial cells
MM Cunha, ABM Pereira, RC Lino, PR da Silva… - Immunobiology, 2023 - Elsevier
Background Airway epithelial cells are crucial for the establishment of cryptococcosis. In
experimental cryptococcosis, the Th2 immune response is associated with host …
experimental cryptococcosis, the Th2 immune response is associated with host …
[HTML][HTML] The IL-33 receptor (ST2) regulates early IL-13 production in fungus-induced allergic airway inflammation
D Piehler, M Eschke, B Schulze, M Protschka… - Mucosal …, 2016 - Elsevier
Allergic airway inflammation (AAI) in response to environmental antigens is an increasing
medical problem, especially in the Western world. Type 2 interleukins (IL) are central in the …
medical problem, especially in the Western world. Type 2 interleukins (IL) are central in the …
IL-22 and IL-23 regulates the anticryptococcal response during Cryptococcus deuterogattii infection
I Diniz-Lima, A Gomes, M Medeiros… - iScience, 2024 - cell.com
Cryptococcosis is a neglected fungal disease that causes many deaths annually, is primarily
caused by Cryptococcus neoformans and Cryptococcus gattii species. They are …
caused by Cryptococcus neoformans and Cryptococcus gattii species. They are …