Continued usage of cocaine is determined by genetic, conditioned and homeostatic factors,
while it is reinforced by drug-induced reward and the emotionally negative state of drug …

The acute responses to cocaine and its withdrawal contribute to cocaine dependence and
potentiate relapse, with gender being one of the genetic factors affecting the outcome. Here …

The zebrafish (Danio rerio) is rapidly becoming a popular model species in behavioral
neuroscience research. Zebrafish behavior is robustly affected by environmental and …

Mounting evidence implicates the zebrafish (Danio rerio) as a promising model species for
reward and addiction research. Modeling drug abuse-related behavior in both adult and …

Zebrafish (Danio rerio) larvae have been suggested as vertebrate model to complement or
even replace mammals for rapidly assessing behavioral effects of psychoactive drugs. Yet …

Understanding the molecular basis of addiction could be greatly aided by using forward
genetic manipulation to lengthen the list of candidate genes involved in this complex …

Recent reports make use of the zebrafish to study complex behavior such as addiction,
anxiety, or learning and memory. We have established reliable tests and appropriate …

Zebrafish (Danio rerio) have been used as a model organism to explore the genetic basis for
responsiveness to addictive drugs like cocaine. However, very little is known about how the …

Addiction is a complex psychiatric disorder considered to be a disease of the brain's natural
reward reinforcement system. Repeated stimulation of thereward'pathway leads to adaptive …

Zebrafish are becoming more widely used to study neurobehavioral pharmacology. We
have developed a method to assess novel environment diving behavior of zebrafish as a …