DNA methylation methods: Global DNA methylation and methylomic analyses

S Li, TO Tollefsbol - Methods, 2021 - Elsevier
DNA methylation provides a pivotal layer of epigenetic regulation in eukaryotes that has
significant involvement for numerous biological processes in health and disease. The …

[HTML][HTML] A Comparison of the Whole Genome Approach of MeDIP-Seq to the Targeted Approach of the Infinium HumanMethylation450 BeadChip® for Methylome …

C Clark, P Palta, CJ Joyce, C Scott, E Grundberg… - PloS one, 2012 - journals.plos.org
DNA methylation is one of the most studied epigenetic marks in the human genome, with the
result that the desire to map the human methylome has driven the development of several …

[HTML][HTML] MethMarker: user-friendly design and optimization of gene-specific DNA methylation assays

P Schüffler, T Mikeska, A Waha, T Lengauer, C Bock - Genome biology, 2009 - Springer
DNA methylation is a key mechanism of epigenetic regulation that is frequently altered in
diseases such as cancer. To confirm the biological or clinical relevance of such changes …

The methylome: approaches for global DNA methylation profiling

S Beck, VK Rakyan - Trends in Genetics, 2008 - cell.com
DNA methylation plays a critical role in genome function both in health and disease. Almost
60 years after the discovery of 5-methyl cytosine and∼ 25 years since the discovery that …

Whole-genome DNA methylation profiling using MethylCap-seq

AB Brinkman, F Simmer, K Ma, A Kaan, J Zhu… - Methods, 2010 - Elsevier
MethylCap-seq is a robust procedure for genome-wide profiling of DNA methylation. The
approach consists of the capture of methylated DNA using the MBD domain of MeCP2, and …

A Bayesian deconvolution strategy for immunoprecipitation-based DNA methylome analysis

TA Down, VK Rakyan, DJ Turner, P Flicek, H Li… - Nature …, 2008 - nature.com
DNA methylation is an indispensible epigenetic modification required for regulating the
expression of mammalian genomes. Immunoprecipitation-based methods for DNA …

Methylated DNA immunoprecipitation sequencing (MeDIP-seq): Principles and applications

JL Neary, MA Carless - Epigenetics Methods, 2020 - Elsevier
Methyl-DNA immunoprecipitation is used in combination with next generation sequencing
(MeDIP-seq) as a genome-wide approach to enrich for and analyze methylated DNA …

[HTML][HTML] DMRforPairs: identifying differentially methylated regions between unique samples using array based methylation profiles

MA Rijlaarsdam, YG van der Zwan, LCJ Dorssers… - BMC …, 2014 - Springer
Background Array based methylation profiling is a cost-effective solution to study the
association between genome methylation and human disease & development. Available …

Methods in DNA methylation profiling

T Zuo, B Tycko, TM Liu, HJL Lin, THM Huang - Epigenomics, 2009 - Taylor & Francis
Metastable and somatically heritable patterns of DNA methylation provide an important level
of genomic regulation. In this article, we review methods for analyzing these genome-wide …

Conservation and divergence of DNA methylation in eukaryotes: new insights from single base-resolution DNA methylomes

Z Su, L Han, Z Zhao - Epigenetics, 2011 - Taylor & Francis
DNA methylation is one of the most important heritable epigenetic modifications of the
genome and is involved in the regulation of many cellular processes. Aberrant DNA …