Investigation of methylation and gene expression in placenta of pregnancies conceived by assisted reproductive technology (ART)

S Sakian - 2011 - open.library.ubc.ca
With the increasing use of assisted reproductive techniques (ART) every year, concerns
have been raised regarding the possible effect these procedures have on the health of the …

Altered gene expression of H19 and IGF2 in placentas from ART pregnancies

S Sakian, K Louie, EC Wong, J Havelock, S Kashyap… - Placenta, 2015 - Elsevier
Introduction The aim of this study is to determine whether the gene expression and
associated DNA methylation regulation of H19 and IGF2 are altered in placentas conceived …

[HTML][HTML] DNA methylation at H19/IGF2 ICR1 in the placenta of pregnancies conceived by in vitro fertilization and intracytoplasmic sperm injection

EC Wong, C Hatakeyama, WP Robinson, S Ma - Fertility and sterility, 2011 - Elsevier
DNA methylation at H19 ICR1 was investigated in the placenta from pregnancies conceived
by in vitro fertilization, intracytoplasmic sperm injection, and from natural conception. Our …

Abnormal methylation patterns at the IGF2/H19 imprinting control region in phenotypically normal babies conceived by assisted reproductive technologies

X Shi, Y Ni, H Zheng, S Chen, M Zhong, F Wu… - European Journal of …, 2011 - Elsevier
OBJECTIVE: To evaluate epigenetic risks linked to assisted reproductive technologies (ART)
by determining the methylation status of the IGF2/H19 imprinting control region (ICR) in …

[引用][C] Genomic imprinting disorders and birth defects in pregnancies conceived with assisted reproductive technology (ART)

K Bianco, ME Norton, VT Angeles, RR Pera - American Journal of …, 2006 - ajog.org
Objective Genomic imprinting refers to differential expression of genes of paternal versus
maternal inheritance. Recent literature, demonstrated that imprinting disorders may be …

Investigation into methylation of imprinted genes in children conceived via assisted reproductive technologies (ART) compared to naturally conceived (NC) controls

RN Vincent, KB Dong, EC Wong, LP Cao, S Ma - Fertility and Sterility, 2014 - fertstert.org
Objective To investigate DNA methylation at the KvDMR1, PLAGL1 and PEG10 differentially
methylated regions (DMRs) and the repetitive LINE-1 element in cord blood (CB) and …

Time to re-evaluate ART protocols in the light of advances in knowledge about methylation and epigenetics: an opinion paper

Y Menezo, B Dale, K Elder - Human Fertility, 2018 - Taylor & Francis
DNA methylation is a biochemical process that modifies gene expression without changing
the underlying DNA sequence, and this represents the molecular basis for imprinting and …

Placental imprinting variation associated with assisted reproductive technologies and subfertility

JF Litzky, MA Deyssenroth, TM Everson… - Epigenetics, 2017 - Taylor & Francis
Infertility affects one in 6 couples in developed nations, resulting in an increasing use of
assisted reproductive technologies (ART). Both ART and subfertility appear to be linked to …

Inter-and intra-individual variation in allele-specific DNA methylation and gene expression in children conceived using assisted reproductive technology

N Turan, S Katari, LF Gerson, R Chalian… - PLoS …, 2010 - journals.plos.org
Epidemiological studies have reported a higher incidence of rare disorders involving
imprinted genes among children conceived using assisted reproductive technology (ART) …

O-192 DNA methylation at H19/IGF2 ICR1 in the placenta of pregnancies conceived by IVF and ICSI

PH Vogt, J Schuettler, Z Peng, J Zimmer, C von Hagens… - academic.oup.com
Introduction: The use of assisted reproductive technologies (ART), namely in-vitro
fertilization (IVF) and intracytoplasmic sperm injection (ICSI), has recently caused concerns …