High-altitude cerebral edema: its own entity or end-stage acute mountain sickness?

REF Turner, H Gatterer, M Falla… - Journal of Applied …, 2021 - journals.physiology.org
High-altitude cerebral edema (HACE) and acute mountain sickness (AMS) are
neuropathologies associated with rapid exposure to hypoxia. However, speculation remains …

High altitude cerebral edema and acute mountain sickness: a pathophysiology update

PH Hackett - Hypoxia: into the next millennium, 1999 - Springer
The diagnosis, treatment and prevention of high altitude cerebral edema (HACE) are fairly
well established. The major unresolved issues are 1) the pathophysiology, 2) the individual …

Frontiers of hypoxia research: acute mountain sickness

RC Roach, PH Hackett - Journal of Experimental Biology, 2001 - journals.biologists.com
Traditionally, scientists and clinicians have explored peripheral physiological responses to
acute hypoxia to explain the pathophysiological processes that lead to acute mountain …

Magnetic resonance imaging evidence of cytotoxic cerebral edema in acute mountain sickness

K Kallenberg, DM Bailey, S Christ… - Journal of Cerebral …, 2007 - journals.sagepub.com
The present study applied T2-and diffusion-weighted magnetic resonance imaging to
examine if mild cerebral edema and subsequent brain swelling are implicated in the …

[HTML][HTML] Systemic pro-inflammatory response facilitates the development of cerebral edema during short hypoxia

TT Song, YH Bi, YQ Gao, R Huang, K Hao, G Xu… - Journal of …, 2016 - Springer
Background High-altitude cerebral edema (HACE) is the severe type of acute mountain
sickness (AMS) and life threatening. A subclinical inflammation has been speculated, but the …

High altitude cerebral edema

PH Hackett, RC Roach - High altitude medicine & biology, 2004 - liebertpub.com
This review focuses on the epidemiology, clinical description, pathophysiology, treatment,
and prevention of high altitude cerebral edema (HACE). HACE is an uncommon and …

[HTML][HTML] Emerging concepts in acute mountain sickness and high-altitude cerebral edema: from the molecular to the morphological

DM Bailey, P Bärtsch, M Knauth… - Cellular and Molecular …, 2009 - Springer
Acute mountain sickness (AMS) is a neurological disorder that typically affects mountaineers
who ascend to high altitude. The symptoms have traditionally been ascribed to intracranial …

The cerebral etiology of high-altitude cerebral edema and acute mountain sickness

PH Hackett - Wilderness & environmental medicine, 1999 - Elsevier
Acute mountain sickness (AMS) and high-altitude cerebral edema (HACE) are essentially
neurological disorders. The five symptoms included in the Lake Louise AMS symptom score …

Early brain swelling in acute hypoxia

DJ Dubowitz, EAW Dyer… - Journal of Applied …, 2009 - journals.physiology.org
Acute mountain sickness (AMS) and high-altitude cerebral edema share common clinical
characteristics, suggesting cerebral swelling may be an important factor in the …

The cerebral effects of ascent to high altitudes

MH Wilson, S Newman, CH Imray - The Lancet Neurology, 2009 - thelancet.com
Cellular hypoxia is the common final pathway of brain injury that occurs not just after
asphyxia, but also when cerebral perfusion is impaired directly (eg, embolic stroke) or …