Flow-induced, inflammation-mediated arterial wall remodeling in the formation and progression of intracranial aneurysms
OBJECTIVE Unruptured intracranial aneurysms (UIAs) are relatively common lesions that
may cause devastating intracranial hemorrhage, thus producing considerable suffering and …
may cause devastating intracranial hemorrhage, thus producing considerable suffering and …
CFD: computational fluid dynamics or confounding factor dissemination? The role of hemodynamics in intracranial aneurysm rupture risk assessment
Image-based computational fluid dynamics holds a prominent position in the evaluation of
intracranial aneurysms, especially as a promising tool to stratify rupture risk. Current …
intracranial aneurysms, especially as a promising tool to stratify rupture risk. Current …
Hemodynamic stress, inflammation, and intracranial aneurysm development and rupture: a systematic review
F Signorelli, S Sela, L Gesualdo, S Chevrel, F Tollet… - World neurosurgery, 2018 - Elsevier
Background There seems to be a pathogenetic link between hemodynamics and
inflammatory arterial wall alteration leading to the development and rupture of intracranial …
inflammatory arterial wall alteration leading to the development and rupture of intracranial …
Role of fluid dynamics and inflammation in intracranial aneurysm formation
374 Circulation January 21, 2014 to vascular aneurysms, we surmise that aneurysm-
protective flows and wall states maintain vascular homeostasis throughout the cerebral tree …
protective flows and wall states maintain vascular homeostasis throughout the cerebral tree …
The association between hemodynamics and wall characteristics in human intracranial aneurysms: a review
Hemodynamics plays a key role in the natural history of intracranial aneurysms (IAs).
However, studies exploring the association between aneurysmal hemodynamics and the …
However, studies exploring the association between aneurysmal hemodynamics and the …
Potential therapeutic strategies for intracranial aneurysms targeting aneurysm pathogenesis
Z Liu, K Ajimu, N Yalikun, Y Zheng, F Xu - Frontiers in Neuroscience, 2019 - frontiersin.org
Subarachnoid hemorrhage resulting from intracranial aneurysms (IAs) is associated with
high rates of morbidity and mortality. Although trigger mechanisms in the pathogenesis of …
high rates of morbidity and mortality. Although trigger mechanisms in the pathogenesis of …
High WSS or low WSS? Complex interactions of hemodynamics with intracranial aneurysm initiation, growth, and rupture: toward a unifying hypothesis
Increasing detection of unruptured intracranial aneurysms, catastrophic outcomes from
subarachnoid hemorrhage, and risks and cost of treatment necessitate defining objective …
subarachnoid hemorrhage, and risks and cost of treatment necessitate defining objective …
Multivariate analysis of hemodynamic parameters on intracranial aneurysm initiation of the internal carotid artery
K Sunderland, J Jiang - Medical engineering & physics, 2019 - Elsevier
Although fluctuating hemodynamic wall stressors are known to impact intracranial
aneurysms (IA) initiation, specificity of those stressors has not been evaluated. In this study …
aneurysms (IA) initiation, specificity of those stressors has not been evaluated. In this study …
Hemodynamic mechanisms underlying cerebral aneurysm pathogenesis
DL Penn, RJ Komotar, ES Connolly - Journal of Clinical Neuroscience, 2011 - Elsevier
Intracranial aneurysms and associated subarachnoid hemorrhage (SAH) are predominant
cerebrovascular disorders that present a significant public health risk through high rates of …
cerebrovascular disorders that present a significant public health risk through high rates of …
The link between hemodynamics and wall structure in cerebral aneurysms
X Duan - 2016 - search.proquest.com
Intracranial aneurysms (IAs) are pathological enlargements of the walls of cerebral arteries.
Rupture of aneurysms causes 80% of subarachnoid hemorrhages. It is generally accepted …
Rupture of aneurysms causes 80% of subarachnoid hemorrhages. It is generally accepted …