Recent studies have suggested that long standing elevated wall shear stress might
degenerate the arterial wall and be involved in the pathogenesis of intracranial aneurysm …

Background Understanding the risk factors leading to intracranial aneurysm (IA) rupture
have still not been fully clarified. They are vital for proper medical guidance of patients …

Background and Purpose—Evolution of intracranial aneurysmal disease is known to be
related to hemodynamic forces acting on the vessel wall. Low wall shear stress (WSS) has …

BACKGROUND: Intracranial aneurysms (IAs) occur more frequently at certain bifurcations
than at others. Hemodynamic stress, which promotes aneurysm formation in animal models …

The central nervous system is an immunologically active environment where several
components of the immune and inflammatory response interact among them and with the …

BACKGROUND AND PURPOSE: Saccular intracranial aneurysm is a common disease that
may cause devastating intracranial hemorrhage. Hemodynamics, wall remodeling, and wall …

The physiological mechanisms that give rise to the inception and development of a cerebral
aneurysm are accepted to involve the interplay between the local mechanical forces acting …

Growing knowledge on the pathophysiology of human intracranial aneurysms (IAs) has led
to a deeper understanding of the processes of IA growth and rupture. In past decades …

Intracranial aneurysms pose a significant challenge in neurosurgical practice due to their
potential for rupture with possible catastrophic consequences. The management of these …

We present a novel patient-specific fluid-solid-growth framework to model the
mechanobiological state of clinically detected intracranial aneurysms (IAs) and their …