Germline mutations in the VHL tumour suppressor gene may cause a variety of phenotypes
including von Hippel-Lindau (VHL) disease, familial phaeochromocytoma and inherited …

Abstract Since the Von Hippel–Lindau (VHL) disease tumour suppressor gene VHL was
identified in 1993 as the genetic basis for a rare disorder, it has proved to be of wide medical …

Abstract The Von Hippel–Lindau (VHL) is an inherited neoplasia syndrome caused by the
inactivation of VHL tumor suppressor gene, and somatic mutation of this gene has been …

Germ line mutations of the VHL gene have been identified as the root cause of this disease.
6 Mutations and/or aberrations of the same gene have been identified in the majority of …

Germ line mutations in the VHL tumor-suppressor gene cause von Hippel–Lindau (VHL)
disease, a hereditary neoplastic disease associated with clear-cell renal-cell carcinomas …

Abstract The von Hippel-Lindau tumor suppressor gene (VHL), which resides on
chromosome 3p25, is mutated or silenced in> 50% of sporadic clear cell renal cell …

von Hippel-Lindau disease is a hereditary cancer syndrome predisposing carriers to the
development of a panel of highly vascularized tumors such as central nervous system and …

Abstract Von Hippel-Lindau syndrome (VHLS) is a rare hereditary neoplastic disorder
caused by mutations in the vhl gene leading to the development of tumors in several organs …

Germ line VHL tumor suppressor gene loss-of-function mutations cause von Hippel-Lindau
disease, which is associated with an increased risk of central nervous system …

Abstract von Hippel–Lindau (VHL) disease is a hereditary tumor syndrome predisposing to
multifocal bilateral renal cell carcinomas (RCCs), pheochromocytomas, and pancreatic …