A large body of evidence demonstrates that DNA methylation plays a role in gene regulation
in animal cells. Not only is there a correlation between gene transcription and …

Publisher Summary The chapter discusses on the DNA methylation and its possible
biological roles. The pattern of DNA methylation is species-specific. In the DNA of some …

The occurrence of 5-methylcytosine in DNA was first described in 1948 by Hotchkiss (see
first chapter). Recognition of its possible physiologi cal role in eucaryotes was first …

Summary Eukaryotic genomes contain 5-methylcytosine (5mC) as a rare base. 5mC arises
by postsynthetic modification of cytosine and occurs, at least in animals, predominantly in …

Publisher Summary This chapter discusses the deoxyribonucleic acid (DNA) methylation
from embryo to adult. The existence of tissue-specific methylation patterns and the results of …

DNA methyltransferase is needed for normal development, perhaps because DNA
methylation plays a part in the control of gene activity. It is clear that the methylation of …

DNA methylation: A molecular lock: Current Biology Skip to Main Content Advertisement Current
Biology This journal offers authors two options (open access or subscription) to publish research …

Recent advances have expanded our understanding of the processes underlying the
establishment, maintenance, and elaboration of DNA methylation patterns in eukaryotes …

The occurrence of 5-methylcytosine (m S Cyt) and Nr-methyladenine (m6Ade) as minor
bases in DNA has been known for more than 35 years [1-3]. The fact that DNA methylation is …

An obstacle to progress in understanding eukaryotic DNA methylation has been the lack of a
good genetic systemthe most favorable eukaryotes for genetic analysis (yeasts …