Genome‐wide DNA methylation profiling of gastric cardia cancer

R Lin, Y Qian, J Zhang, D Xia, D Guo… - Journal of …, 2023 - Wiley Online Library
Abstract Background and Aim Aberrant DNA methylation has been found in various cancer
types including gastric cancer, yet the genome‐wide DNA methylation profile of gastric …

Analysis of the clinical significance of DNA methylation in gastric cancer based on a genome-wide high-resolution array

WL Fang, MH Chen, KH Huang, SC Chang, CH Lin… - Clinical …, 2019 - Springer
Background Aberrant DNA methylation is involved in gastric carcinogenesis and may serve
as a useful biomarker in the diagnosis and detection of gastric cancer (GC) recurrence …

Genome-wide DNA methylation profiling identifies epigenetic signatures of gastric cardiac intestinal metaplasia

R Lin, C Li, Z Liu, R Wu, J Lu - Journal of Translational Medicine, 2020 - Springer
Background Measuring the DNA methylome may offer the opportunity to identify novel
disease biomarkers and insights into disease mechanisms. Although aberrant DNA …

[HTML][HTML] Integrated epigenomic analyses of enhancer as well as promoter regions in gastric cancer

SJ Baek, M Kim, DH Bae, JH Kim, HJ Kim, ME Han… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Abnormal DNA methylation is an epigenetic mechanism that promotes gastric
carcinogenesis. While the abnormal methylation at promoter regions has been …

Identification of DNA methylation changes associated with human gastric cancer

JH Park, J Park, JK Choi, J Lyu, MG Bae, YG Lee… - BMC medical …, 2011 - Springer
Background Epigenetic alteration of gene expression is a common event in human cancer.
DNA methylation is a well-known epigenetic process, but verifying the exact nature of …

Genome-wide identification and characterization of DNA methylation and long non-coding RNA expression in gastric cancer

P Song, L Wu, W Guan - Frontiers in genetics, 2020 - frontiersin.org
Abnormal DNA methylation, an epigenetic modification, has increasingly been linked to the
pathogenesis of many human cancers. However, there has been little focus on the DNA …

DNA methylation profiling identifies epigenetic signatures of early gastric cancer

Z Shi, X Guo, X Hu, R Li, X Li, J Lu, M Jin, X Jiang - Virchows Archiv, 2024 - Springer
Research on the DNA methylation status of gastric cancer (GC) has primarily focused on
identifying invasive GC to develop biomarkers for diagnostic. However, DNA methylation in …

DNA methylation genome-wide analysis in remnant and primary gastric cancers

K Sugimoto, T Ito, A Hulbert, C Chen, H Orita, M Maeda… - Gastric Cancer, 2019 - Springer
Background Although primary (PGC) and remnant gastric cancers (RGC) both originate from
the same gastrointestinal organ, they have very distinct clinicopathological behaviors. We …

Whole genome MBD-seq and RRBS analyses reveal that hypermethylation of gastrointestinal hormone receptors is associated with gastric carcinogenesis

HJ Kim, TW Kang, K Haam, M Kim, SK Kim… - … & Molecular Medicine, 2018 - nature.com
DNA methylation is a regulatory mechanism in epigenetics that is frequently altered during
human carcinogenesis. To detect critical methylation events associated with gastric cancer …

Hypermethylation of EIF4E promoter is associated with early onset of gastric cancer

Y Ge, Q Wu, G Ma, W Shao, H Liu, Q Zhang… - …, 2018 - academic.oup.com
Although gastric cancer (GC) in young adults (≤ 45 years) accounts for fewer than 10% of
newly diagnosed cases, the young patients are more likely to have advanced disease at …