Microevolution of a Standard Strain ofCryptococcus neoformans Resulting in Differences in Virulence and Other Phenotypes

SP Franzot, J Mukherjee, R Cherniak… - Infection and …, 1998 - Am Soc Microbiol
Cryptococcus neoformans is a major fungal pathogen for patients with debilitated immune
systems. However, no information is available on the stability of virulence or of phenotypes …

Morphogenesis of Cryptococcus neoformans

JA Alspaugh, RC Davidson… - Contributions to …, 2000 - books.google.com
First discovered over a century ago, Cryptococcus neoformans is a basidiomycetous yeast
that causes human disease throughout the world [1, 2]. Although this organism grows …

Multiple origins of hybrid strains of Cryptococcus neoformans with serotype AD

J Xu, G Luo, RJ Vilgalys, ME Brandt… - …, 2002 - microbiologyresearch.org
Cryptococcus neoformans is a major pathogen of humans throughout the world. Using
commercial mAbs to capsular epitopes, strains of C. neoformans manifest five distinct …

Serial Isolates of Cryptococcus neoformans from Patients with AIDS Differ in Virulence for Mice

BC Fries, A Casadevall - The Journal of infectious diseases, 1998 - academic.oup.com
Serial isolates of Cryptococcus neoformans from patients with chronic infection can exhibit
minor karyotype changes as a result of chromosome length polymorphism (CLP). This study …

What makes Cryptococcus neoformans a pathogen?

KL Buchanan, JW Murphy - Emerging infectious diseases, 1998 - ncbi.nlm.nih.gov
Life-threatening infections caused by the encapsulated fungal pathogen Cryptococcus
neoformans have been increasing steadily over the past 10 years because of the onset of …

Comparative Analysis of Environmental and Clinical Populations of Cryptococcus neoformans

AP Litvintseva, L Kestenbaum, R Vilgalys… - Journal of clinical …, 2005 - Am Soc Microbiol
Cryptococcus neoformans is a major, global cause of meningoencephalitis in
immunocompromised patients. Despite advances in the molecular epidemiology of C …

Diversity among Strains of Cryptococcus neoformans var. gattii as Revealed by a Sequence Analysis of Multiple Genes and a Chemotype Analysis of Capsular …

T Sugita, R Ikeda, T Shinoda - Microbiology and immunology, 2001 - Wiley Online Library
We demonstrated the diversity of Cryptococcus neoformans var. gattii strains by a sequence
analysis of multiple genes:(i) the intergenic spacer (IGS) 1 and 2 regions of the rRNA …

Phenotypic Switching in Cryptococcus neoformansResults in Changes in Cellular Morphology and Glucuronoxylomannan Structure

BC Fries, DL Goldman, R Cherniak, R Ju… - Infection and …, 1999 - Am Soc Microbiol
Cryptococcus neoformans strains exhibit variability in their capsular polysaccharide, cell
morphology, karyotype, and virulence, but the relationship between these variables is poorly …

Characterization of Cryptococcus neoformans by random DNA amplification

P Ruma, SCA Chen, TC Sorrel… - Letters in applied …, 1996 - Wiley Online Library
Random amplified polymorphic DNA (RAPD) was optimized and used to distinguish
between the varieties and serotypes of Cryptococcus neofirmans. The RAPD technique …

Molecular Identification of Cryptococcus neoformans Serotypes

A Enache-Angoulvant, J Chandenier… - Journal of clinical …, 2007 - Am Soc Microbiol
Cryptococcus neoformans is a fungal pathogen that causes life-threatening infections
primarily in immunocompromised hosts. Based on the genetic characteristics and serologic …