Genomics, convergent neuroscience and progress in understanding autism spectrum disorder
More than a hundred genes have been identified that, when disrupted, impart large risk for
autism spectrum disorder (ASD). Current knowledge about the encoded proteins—although …
autism spectrum disorder (ASD). Current knowledge about the encoded proteins—although …
Autism spectrum disorders: from genes to neurobiology
AJ Willsey, MW State - Current opinion in neurobiology, 2015 - Elsevier
Highlights•High throughput genomic methods are rapidly increasing the pool of ASD
genes.•Heterogeneity, pleiotropy, and brain complexity complicate translation to …
genes.•Heterogeneity, pleiotropy, and brain complexity complicate translation to …
[HTML][HTML] Genetic architecture of autism spectrum disorder: Lessons from large-scale genomic studies
L Choi, JY An - Neuroscience & Biobehavioral Reviews, 2021 - Elsevier
Autism spectrum disorder (ASD) is a neurodevelopmental disorder with a strong genetic
component. Recently developed genomic technologies, including microarray and next …
component. Recently developed genomic technologies, including microarray and next …
Genetic heterogeneity in autism: From single gene to a pathway perspective
JY An, C Claudianos - Neuroscience & Biobehavioral Reviews, 2016 - Elsevier
The extreme genetic heterogeneity of autism spectrum disorder (ASD) represents a major
challenge. Recent advances in genetic screening and systems biology approaches have …
challenge. Recent advances in genetic screening and systems biology approaches have …
Genetic contributions to autism spectrum disorder
A Havdahl, M Niarchou, A Starnawska… - Psychological …, 2021 - cambridge.org
Autism spectrum disorder (autism) is a heterogeneous group of neurodevelopmental
conditions characterized by early childhood-onset impairments in communication and social …
conditions characterized by early childhood-onset impairments in communication and social …
Progress in the genetics of autism spectrum disorder
M Woodbury‐Smith, SW Scherer - Developmental Medicine & …, 2018 - Wiley Online Library
A genetic basis for autism spectrum disorder (ASD) is now well established, and with the
availability of high‐throughput microarray and sequencing platforms, major advances have …
availability of high‐throughput microarray and sequencing platforms, major advances have …
Genetics and genomics of autism spectrum disorder: embracing complexity
S De Rubeis, JD Buxbaum - Human molecular genetics, 2015 - academic.oup.com
Autism spectrum disorder (ASD) is a neurodevelopmental disorder (NDD) characterized by
impairments in social communication and social interaction and the presence of repetitive …
impairments in social communication and social interaction and the presence of repetitive …
Risk factors for autism: translating genomic discoveries into diagnostics
SW Scherer, G Dawson - Human genetics, 2011 - Springer
Autism spectrum disorders (ASDs) are a group of conditions characterized by impairments in
communication and reciprocal social interaction, and the presence of restricted and …
communication and reciprocal social interaction, and the presence of restricted and …
[HTML][HTML] Integrative functional genomic analyses implicate specific molecular pathways and circuits in autism
Genetic studies have identified dozens of autism spectrum disorder (ASD) susceptibility
genes, raising two critical questions:(1) do these genetic loci converge on specific biological …
genes, raising two critical questions:(1) do these genetic loci converge on specific biological …
Genetics of autism spectrum disorder
G Ramaswami, DH Geschwind - Handbook of clinical neurology, 2018 - Elsevier
Autism spectrum disorder (ASD) is a prevalent neurodevelopmental disorder characterized
by impaired social interaction and stereotyped behaviors. ASD has a strong and complex …
by impaired social interaction and stereotyped behaviors. ASD has a strong and complex …