Chronic lymphocytic leukaemia (CLL) is the most common leukaemia in the western world.
In previous studies, various proportion of patients was found to carry CD11b+ or CD11c+ B …

Progressive cases of B-cell chronic lymphocytic leukemia (CLL) are frequently associated
with lymphadenopathy, highlighting a critical role for signals emanating from the tumor …

CD49d and CXCR4 are key determinants of interactions between chronic lymphocytic
leukemia (CLL) tumor cells and their microenvironment. In this study, we investigated the …

CD5 is a transmembrane protein expressed on all T lineage cells and a subset of B cells. It
is known that CD5 is physically associated with the T-cell receptor and B-cell receptor …

Several chemokines/chemokine receptors such as CCR7, CXCR4 and CXCR5 attract
chronic lymphocytic leukemia (CLL) cells to specific microenvironments. Here we have …

B-cell chronic lymphocytic leukemia (CLL) is characterized by differential BCR signaling and
autoimmune complications. Complement modulates B-cell function via C3d and CD21 cross …

We previously reported that B-cell receptor (BCR) signaling promoted a concomitant
decrease of CXCR4 and CD62L membrane expression only in progressive cases of chronic …

Abstract 3593 Unlike other hematologic disorders, chronic lymphocytic leukemia (CLL)
exhibits remarkable heterogeneity in the rates of disease progression among cases. CLL …

CD49d is a remarkable prognostic biomarker of chronic lymphocytic leukemia (CLL). The
cutoff value for the extensively validated 30% of positive CLL cells is able to separate CLL …

The expression and role of CR3 (CD11b/CD18) and CR4 (CD11c/CD18) in B cells are not
yet explored in contrast to myeloid cells, where these β 2-integrin type receptors are known …