Epidemiological data and results from animal studies indicate that imbalances in maternal
nutrition impact the expression of metabolic disorders in the offspring. We tested the …

Significant alterations in maternal nutrition may induce long‐term metabolic consequences
in offspring, in particular obesity and leptin and insulin resistance. Although maternal …

Abstract Background/Objectives The current obesity epidemic has spurred exploration of the
developmental origin of adult heath and disease. A mother's dietary choices and health can …

Several studies indicate that maternal undernutrition sensitizes the offspring to the
development of metabolic disorders, such as obesity. Using a model of perinatal maternal …

An intrauterine environment may play a role in predisposing a developing fetus to metabolic
diseases during adulthood. We investigated the hypothesis that a maternal diet high in ω-6 …

Maternal obesity is increasing, and it is known that the intrauterine experience programs
fetal and newborn metabolism. However, the relative contributions of pre-or postnatal factors …

Excessive gestational weight gain and maternal obesity have both been associated with
increased incidence of obesity and metabolic disorder in offspring in both humans and …

Maternal overnutrition prior to and during gestation causes pronounced metabolic
dysfunction in the adult offspring. However, less is known about metabolic adaptations in the …

Epidemiological and animal studies suggest that diet-induced epigenetic modifications in
early life can contribute to development of the metabolic syndrome in adulthood. We …

While adult lifestyle factors undoubtedly contribute to the incidence of obesity and its
attendant disorders, mounting evidence suggests that programming of obesity may occur …