Background An animal model commonly used to investigate pathways and potential
therapeutic interventions relevant to abdominal aortic aneurysm (AAA) involves …

Objective—Abdominal aortic aneurysms (AAAs) are common, but their exact pathogenesis
remains unknown and no specific medical therapies are available. We sought to evaluate …

Abdominal aortic aneurysm (AAA) is a life-threatening disease associated with high
morbidity, and high mortality in the event of aortic rupture. Major advances in open surgical …

Mouse models that mimic human diseases are important tools for investigating underlying
mechanisms in many disease states. Although the demand for these models is high, there …

Abdominal aortic aneurysms (AAAs) are local dilations of infrarenal segment of aortas.
Molecular mechanisms underlying the pathogenesis of AAA remain not fully clear. However …

Abdominal aortic aneurysm (AAA) is a lethal degenerative vascular disease that affects,
mostly, the elder population, with a high mortality rate (> 80%) upon rupture. It features a …

An abdominal aortic aneurysm (AAA) is a dilatation of the abdominal aorta with a diameter of
at least 3.0 cm. AAAs are often asymptomatic and are discovered as incidental findings in …

Atherosclerosis is one of the primary causes of cardiovascular disease and mortality. This
chronic immunometabolic disease evolves during decades in humans and encompasses …

Objective Abdominal aortic aneurysm (AAA) is a condition that mainly affects elderly men. At
present, there is no effective medical therapy that can retard aneurysm growth or prevent …

Atherosclerosis is a significant cause of morbidity and mortality globally. Many animal
models have been developed to study atherosclerosis, and permit experimental conditions …