Valproic acid (VPA), a branched short‐chain fatty acid, is widely used as an antiepileptic
drug and a mood stabilizer. Antiepileptic properties have been attributed to inhibition of …

Valproic acid, a branching short chain fatty acid, is a popular drug to treat epilepsy and acts
as a mood-stabilizing drug. The obstruction of ion channels and Gamma Amino Butyrate …

Valproic acid (VPA) is a well-established anticonvulsant drug discovered serendipitously
and marketed for the treatment of epilepsy, migraine, bipolar disorder and neuropathic pain …

The manuscript focuses on structure-activity relationship studies of CNS-active compounds
derived from valproic acid (VPA) that have the potential to become second-generation VPA …

After more than a century from its discovery, valproic acid (VPA) still represents one of the
most efficient antiepileptic drugs (AEDs). Pre and post-synaptic effects of VPA depend on a …

Valproic acid (VPA) is a branched short-chain fatty acid derived from naturally occurring
valeric acid. VPA is used primarily in the treatment of epilepsy and seizures, but is also used …

Valproic acid (VPA) is considered to be a drug of first choice and one of the most frequently-
prescribed antiepileptic drugs worldwide for the therapy of generalized and focal epilepsies …

Valproate, one of the major antiepileptic drugs used today, has besides its wide use in both
generalized and partial epilepsies, several new approved indications including the …

Sodium valproate, or Epilim, has been widely used as a broad spectrum, anticonvulsant
drug for over 40 years and exhibits a good safety profile. Some of the actions of valproate …

Sodium valproate (VPA) belongs to the group of simple branched-chain fatty acids and due
its anticonvulsive activity is broadly applied in the treatment of epilepsy. We previously …