Prostate cancers are highly prevalent in the developed world, with inheritable risk
contributing appreciably to tumour development. Genomic heterogeneity within individual …

Traversing the genomic landscape of prostate cancer from diagnosis to death | Nature
Genetics Skip to main content Thank you for visiting nature.com. You are using a browser …

Recent genetics and genomics studies of prostate cancer have helped to clarify the genetic
basis of this common but complex disease. Genome-wide studies have detected numerous …

Prostate cancer is a common malignancy in men, with a markedly variable clinical course.
Somatic alterations in DNA drive the growth of prostate cancers and may underlie the …

Background With continuous progress over the past few decades in understanding
diagnosis, treatment, and genetics, much has been learned about the prostate cancer …

Objectives Prostate cancer has a variable clinical course, and molecular characterization
has revealed striking mutational heterogeneity that may underlie the unpredictable clinical …

From a clinical, morphological and molecular perspective, prostate cancer is a
heterogeneous disease. Primary prostate cancers are often multifocal, having …

Although prostate cancer is the most common malignancy to affect men in the Western
world, the molecular mechanisms underlying its development and progression remain …

The remarkable variation in prostate cancer clinical behavior represents an opportunity to
identify and understand molecular features that can be used to stratify patients into clinical …

Over the past several years, analyses of data from high-throughput studies have elucidated
many fundamental insights into prostate cancer biology. These insights include the …