[HTML][HTML] Novel experimental model of enlarging abdominal aortic aneurysm in rabbits

Y Bi, H Zhong, K Xu, X Qi, Z Zhang, G Wu… - Journal of vascular …, 2015 - Elsevier
Objective This study tested the hypothesis that an experimental model of abdominal aortic
aneurysm in rabbits results in progressive enlargement when induced by a combination of …

[HTML][HTML] Performance of a modified rabbit model of abdominal aortic aneurysm induced by topical application of porcine elastase: 5-month follow-up study

Y Bi, H Zhong, K Xu, Y Ni, X Qi, Z Zhang, W Li - European Journal of …, 2013 - Elsevier
OBJECTIVES: To modify the method for creating an abdominal aortic aneurysm in rabbits,
and to study its performance. MATERIALS AND METHODS: A total of 24 New Zealand white …

[HTML][HTML] Hemodynamics and pathology of an enlarging abdominal aortic aneurysm model in rabbits

H Chen, Y Bi, S Ju, L Gu, X Zhu, X Han - PloS one, 2018 - journals.plos.org
Hemodynamics may play an essential role in the initiation and progression of abdominal
aortic aneurysm (AAA). We aimed to study the mechanism of self-healing process by the …

[HTML][HTML] Rabbit aortic aneurysm model with enlarging diameter capable of better mimicking human aortic aneurysm disease

Y Bi, H Chen, Y Li, Z Yu, X Han, J Ren - PloS one, 2018 - journals.plos.org
The self-healing phenomenon can be found in the elastase-induced abdominal aortic
aneurysm (AAA) model, and an enlarging AAA model was successfully induced by …

A rabbit model of abdominal aortic aneurysm associated with intimal thickening

M Matsushita, H Kobayashi, K Oda… - European Surgical …, 1999 - karger.com
A model of abdominal aortic aneurysm with intimal thickening was developed in the rabbit. A
segment of the abdominal aorta just proximal to the bifurcation (1 or 2 cm in length) was …

[HTML][HTML] A novel rat model of abdominal aortic aneurysm using a combination of intraluminal elastase infusion and extraluminal calcium chloride exposure

A Tanaka, T Hasegawa, Z Chen, Y Okita… - Journal of Vascular …, 2009 - Elsevier
OBJECTIVE: An ideal animal model of abdominal aortic aneurysm (AAA) is of great
importance for clarifying unknown complex mechanisms of the pathogenesis. We introduce …

Aneurysm induced by periarterial application of elastase heals spontaneously.

N Origuchi, H Shigematsu, N Izumiyama… - … angiology: a journal …, 1998 - europepmc.org
Background The pathogenesis of aortic aneurysms remains largely unknown, despite
aneurysmal rupture being an increasingly common catastrophe. Methods This study was …

A modified murine abdominal aortic aneurysm rupture model using elastase perfusion and angiotensin II infusion

J Yue, L Yin, J Shen, Z Liu - Annals of Vascular Surgery, 2020 - Elsevier
Background The perfused elastase AAA model and subcutaneous Angiotensin II infusion
AAA model are widely used murine AAA models. We modified these two current models and …

Morphologic changes in the aorta during elastase infusion in the rat aneurysm model

T Yamaguchi, M Yokokawa, M Suzuki… - Journal of Surgical …, 2001 - Elsevier
Background. The morphologic changes in the aorta during elastase infusion, which have not
previously been investigated, were examined in the rat abdominal aortic aneurysm model …

[HTML][HTML] Creation of Abdominal Aortic Aneurysms in Sheep by Extrapolation of Rodent Models: Is It Feasible?

P Verbrugghe, J Verhoeven, M Clijsters… - Annals of Vascular …, 2018 - Elsevier
Background Abdominal aortic aneurysms (AAAs) are a potentially deathly disease, needing
surgical or endovascular treatment. To evaluate potentially new diagnostic tools and …