Male factor infertility has been associated with abnormal DNA methylation at imprinted
genes. Little information is available on the status of imprinting in the sperm of men with …

Background Male infertility is a complex disease caused by a combination of genetic,
environmental, and lifestyle factors. Abnormal epigenetic programming has been proposed …

Imprinting errors have been described in spermatozoa from infertile patients with
oligozoospermia and azoospermia. However, little is known about methylation of imprinted …

Imprinted genes are expressed either from the paternal or the maternal allele, because the
other allele has been silenced in the mother's or father's germline. Imprints are characterized …

OBJECTIVE: To evaluate the associations between proper protamine incorporation and
DNA methylation at imprinted loci. DESIGN: Experimental research study. SETTING …

Background Altered sperm DNA methylation patterns of imprinted genes as well as certain
spermatogenesis-related genes has been proposed as a possible mechanism of male …

OBJECTIVE: To study the methylation imprinting marks of two oppositely imprinted genes,
H19 and MEST/PEG1, in human testicular spermatozoa from azoospermic patients with …

Disorders in genetic imprinting are discussed as potential genetic risk in assisted
reproduction technology (ART), where most of the natural selection mechanisms are …

Recent studies have shown associations of aberrant DNA methylation in spermatozoa with
idiopathic infertility. The analysis of DNA methylation of specific genes could therefore serve …

Recent studies suggest that assisted reproductive technologies (ART), which involve the
isolation, handling and culture of gametes and early embryos, are associated with an …