In vitro cytotoxicity and genotoxicity studies of titanium dioxide (TiO2) nanoparticles in Chinese hamster lung fibroblast cells

M Hamzeh, GI Sunahara - Toxicology in Vitro, 2013 - Elsevier
There are increasing safety concerns about the development and abundant use of
nanoparticles. The unique physical and chemical characteristics of titanium dioxide (TiO2) …

Cytotoxicity of titanium dioxide nanoparticles in mouse fibroblast cells

CY Jin, BS Zhu, XF Wang, QH Lu - Chemical research in …, 2008 - ACS Publications
Nanotitanium dioxide (TiO2) is an important industrial material that is widely used as an
additive in cosmetics, pharmaceuticals, and food colorants. Although the small size of the …

Cytotoxicity of different sized TiO2 nanoparticles in mouse macrophages

J Zhang, W Song, J Guo, J Zhang… - Toxicology and …, 2013 - journals.sagepub.com
With large-scale production and wide application of nano-titanium oxide (TiO2), its health
hazard has attracted extensive attention worldwide. In this study, mouse macrophages (Ana …

Investigation of genotoxic and cytotoxic effects of micro-and nanosized titanium dioxide in six organs of mice in vivo

LP Sycheva, VS Zhurkov, VV Iurchenko… - … /Genetic Toxicology and …, 2011 - Elsevier
Titanium dioxide is manufactured worldwide in large quantities for use in a wide range of
applications including as food additives, in cosmetics and pigments for coloring ingested …

Genotoxic evaluation of titanium dioxide nanoparticles in vivo and in vitro

Z Chen, Y Wang, T Ba, Y Li, J Pu, T Chen, Y Song… - Toxicology letters, 2014 - Elsevier
With the extensive application of titanium dioxide (TiO 2) nanoparticles (NPs) in food
industry, there is a rising debate concerning the possible risk associated with exposure to …

Evaluation of cytotoxic, genotoxic and inflammatory response in human alveolar and bronchial epithelial cells exposed to titanium dioxide nanoparticles

CL Ursini, D Cavallo, AM Fresegna… - Journal of Applied …, 2014 - Wiley Online Library
The toxicity of titanium dioxide nanoparticles (TiO2‐NPs), used in several applications,
seems to be influenced by their specific physicochemical characteristics. Cyto‐genotoxic …

[HTML][HTML] Role of the crystalline form of titanium dioxide nanoparticles: Rutile, and not anatase, induces toxic effects in Balb/3T3 mouse fibroblasts

C Uboldi, P Urbán, D Gilliland, E Bajak… - Toxicology in vitro, 2016 - Elsevier
The wide use of titanium dioxide nanoparticles (TiO 2 NPs) in industrial applications
requires the investigation of their effects on human health. In this context, we investigated …

Long-term exposure of A549 cells to titanium dioxide nanoparticles induces DNA damage and sensitizes cells towards genotoxic agents

L Armand, A Tarantini, D Beal, M Biola-Clier… - …, 2016 - Taylor & Francis
Abstract Titanium dioxide nanoparticles (TiO2-NPs) are one of the most produced NPs in the
world. Their toxicity has been studied for a decade using acute exposure scenarios, ie high …

Cyto-and genotoxicity of ultrafine TiO2 particles in cultured human lymphoblastoid cells

JJ Wang, BJS Sanderson, H Wang - Mutation Research/Genetic Toxicology …, 2007 - Elsevier
Titanium dioxide is frequently used in the production of paints, paper, plastics, welding rod-
coating material, and cosmetics, because of its low toxicity. However, recent studies have …

Impact of anatase titanium dioxide nanoparticles on mutagenic and genotoxic response in Chinese hamster lung fibroblast cells (V-79): the role of cellular uptake

AK Jain, VA Senapati, D Singh, K Dubey… - Food and chemical …, 2017 - Elsevier
The unique physico-chemical properties of nano crystalline anatase titanium dioxide
nanoparticles (TiO 2 NPs) render them with different biological and chemical activities …