Amyloid-β alters the DNA methylation status of cell-fate genes in an Alzheimer's disease model
N Taher, C McKenzie, R Garrett… - Journal of …, 2014 - content.iospress.com
Alzheimer's disease (AD) is characterized by neurofibrillary tangles and extracellular
amyloid-β plaques (Aβ). Despite ongoing research, some ambiguity remains surrounding …
amyloid-β plaques (Aβ). Despite ongoing research, some ambiguity remains surrounding …
DNA methylation in the pathology of Alzheimer's disease: from gene to cognition
Alzheimer's disease (AD) is a debilitating disorder that manifests with amyloid beta plaque
deposition, neurofibrillary tangles, neuronal loss, and severe cognitive impairment. Although …
deposition, neurofibrillary tangles, neuronal loss, and severe cognitive impairment. Although …
Epigenetics in Alzheimer's disease: perspective of DNA methylation
Research over the years has shown that causes of Alzheimer's disease are not well
understood, but over the past years, the involvement of epigenetic mechanisms in the …
understood, but over the past years, the involvement of epigenetic mechanisms in the …
Age-related epigenetic changes in hippocampal subregions of four animal models of Alzheimer's disease
R Lardenoije, DLA van den Hove, M Havermans… - Molecular and Cellular …, 2018 - Elsevier
Both aging and Alzheimer's disease (AD) are associated with widespread epigenetic
changes, with most evidence suggesting global hypomethylation in AD. It is, however …
changes, with most evidence suggesting global hypomethylation in AD. It is, however …
Epigenetic Changes in Alzheimer's Disease: DNA Methylation and Histone Modification
Alzheimer's disease (AD) is a devastating neurodegenerative disorder characterized by
progressive cognitive decline and memory loss, imposing a significant burden on affected …
progressive cognitive decline and memory loss, imposing a significant burden on affected …
Epigenetics in Alzheimer's disease: a focus on DNA modifications
N Coppieters, M Dragunow - Current pharmaceutical design, 2011 - ingentaconnect.com
Epigenetic alterations have been associated with several human diseases including
Alzheimer's disease (AD). AD is a complex neurodegenerative disease characterized by a …
Alzheimer's disease (AD). AD is a complex neurodegenerative disease characterized by a …
[PDF][PDF] DNA methylation alterations in Alzheimer's disease
AS Yokoyama, JC Rutledge… - Environmental epigenetics, 2017 - academic.oup.com
The observation that Alzheimer's disease (AD) patients with similar and even identical
genetic backgrounds often present with heterogeneous pathologies has prompted the …
genetic backgrounds often present with heterogeneous pathologies has prompted the …
Epigenetic modifications in Alzheimer's disease: cause or effect?
I Piaceri, B Raspanti, A Tedde… - Journal of …, 2014 - journals.sagepub.com
Alzheimer's disease (AD) is a multifactorial disorder induced by a combination of genetic
and environmental factors, and epigenetic modifications could be the key to understand the …
and environmental factors, and epigenetic modifications could be the key to understand the …
Epigenetics and DNA methylomic profiling in Alzheimer's disease and other neurodegenerative diseases
JAY Roubroeks, RG Smith… - Journal of …, 2017 - Wiley Online Library
Recent studies have suggested a role for epigenetic mechanisms in the complex etiology of
various neurodegenerative diseases. In this review, we discuss advances that have been …
various neurodegenerative diseases. In this review, we discuss advances that have been …
DNA methylation signature of human hippocampus in Alzheimer's disease is linked to neurogenesis
M Altuna, A Urdánoz-Casado… - Clinical …, 2019 - Springer
Background Drawing the epigenome landscape of Alzheimer's disease (AD) still remains a
challenge. To characterize the epigenetic molecular basis of the human hippocampus in AD …
challenge. To characterize the epigenetic molecular basis of the human hippocampus in AD …
相关搜索
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- hippocampal subregions alzheimer's disease
- cause or effect alzheimer's disease
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- dna modifications alzheimer's disease
- histone modification alzheimer's disease