Inositol metabolism regulates capsule structure and virulence in the human pathogen Cryptococcus neoformans

Y Wang, M Wear, G Kohli, R Vij, C Giamberardino… - MBio, 2021 - Am Soc Microbiol
The environmental yeast Cryptococcus neoformans is the most common cause of deadly
fungal meningitis in primarily immunocompromised populations. A number of factors …

The aminoalkylindole BML-190 negatively regulates chitosan synthesis via the cyclic AMP/protein kinase A1 pathway in Cryptococcus neoformans

BT Maybruck, WC Lam, CA Specht, MXG Ilagan… - Mbio, 2019 - Am Soc Microbiol
Cryptococcus neoformans can cause fatal meningoencephalitis in patients with AIDS or
other immunocompromising conditions. Current antifungals are suboptimal to treat this …

Antifungal Peptide SP1 Damages Polysaccharide Capsule of Cryptococcus neoformans and Enhances Phagocytosis of Macrophages

Y Liu, Y Zhang, X Zhao, W Lu, Y Zhong… - Microbiology …, 2023 - Am Soc Microbiol
Cryptococcus neoformans is a fungal pathogen which causes nearly half a million deaths
worldwide each year. Under host-relevant conditions, it produces a characteristic …

PRP8 intein in Ajellomycetaceae family pathogens: sequence analysis, splicing evaluation and homing endonuclease activity

RC Theodoro, G Volkmann, XQ Liu… - Fungal Genetics and …, 2011 - Elsevier
Inteins are intervening sequences that are transcribed and translated with flanking host
protein sequences and then self-excised by protein splicing. Bi-functional inteins also …

In vitro Antifungal Activity of a Novel Antimicrobial Peptide AMP-17 Against Planktonic Cells and Biofilms of Cryptococcus neoformans

L Yang, Z Tian, L Zhou, L Zhu, C Sun… - Infection and Drug …, 2022 - Taylor & Francis
Background Cryptococcus neoformans is a common human fungal pathogen in
immunocompromised people, as well as a prevalent cause of meningitis in HIV-infected …

Development of protective inflammation and cell-mediated immunity against Cryptococcus neoformans after exposure to hyphal mutants

B Zhai, KL Wozniak, J Masso-Silva, S Upadhyay… - MBio, 2015 - Am Soc Microbiol
Morphological switch is tightly coupled with the pathogenesis of many dimorphic fungal
pathogens. Cryptococcus neoformans, the major causative agent of cryptococcal meningitis …

Arginase 1 expression by macrophages promotes Cryptococcus neoformans proliferation and invasion into brain microvascular endothelial cells

A Hansakon, C Ngamphiw, S Tongsima… - The Journal of …, 2023 - journals.aai.org
Cryptococcal meningoencephalitis caused by Cryptococcus neoformans infection is the
most common cause of death in HIV/AIDS patients. Macrophages are pivotal for the …

[HTML][HTML] Fungicidal Activity of Recombinant Javanicin against Cryptococcus neoformans Is Associated with Intracellular Target(s) Involved in Carbohydrate and …

S Orrapin, S Roytrakul, N Phaonakrop, S Thaisakun… - Molecules, 2021 - mdpi.com
The occurrence of Cryptococcus neoformans, the human fungal pathogen that primarily
infects immunocompromised individuals, has been progressing at an alarming rate. The …

Quantitative Proteomic Profiling of Cryptococcus neoformans

B Ball, J Geddes‐McAlister - Current protocols in microbiology, 2019 - Wiley Online Library
Cryptococcus neoformans is an opportunistic human fungal pathogen commonly associated
with infection in immunocompromised individuals (eg, patients with HIV/AIDS). Important …

[PDF][PDF] Received: June. 8th 2023 Revised Received: Aug. 16th 2023 Accepted: Aug. 18th 2023 Published Online: Oct. 20th 2023

J JULIAN, R ADAWIYAH, S WAHDINI - J. Infect. Dis, 2024 - journals.athmsi.org
Global mycosis is still a problem. One of these is the cryptococcal disease. A systemic
mycosis brought on by Cryptococcus is called cryptococcosis. Host immunological …