Cryptococcus neoformans is a fungal pathogen that causes disease in
immunocompromised individuals, especially in HIVC/AIDS patients, and organ transplant …

The fungus Cryptococcus neoformans is the causative agent of cryptococcosis, a disease
that is uniformly lethal unless treated with antifungal drugs, yet current regimens are …

The human fungal pathogen, Cryptococcus neoformans, is responsible for deadly infections
among immunocompromised individuals with the evolution of antifungal resistance driving …

Cryptococcus neoformans (C. neoformans) is an important opportunistic fungal pathogen for
pulmonary cryptococcosis. Previously, we demonstrated that CD146 mediated the adhesion …

Cryptococcus species are encapsulated fungi found in the environment that predominantly
cause disease in immunocompromised hosts after inhalation into the lungs. Even with …

In this study we explored the mode of action of KR-72, a 9-O-butyl-13-(4-isopropylbenzyl)
berberine derivative previously shown to exhibit potent antifungal activity against a variety of …

Fungal infections are a global concern and the evolution of intrinsic resistance to current
antifungals presents an alarming problem. For Cryptococcus neoformans, a human fungal …

Cryptococcus neoformans (Cn) is a fungal pathogen, commonly found in urban
environments (Tampieri, 2006) that primarily affects immunocompromised individuals …

The phenotypic plasticity of Cryptococcus neoformans is widely studied and demonstrated in
vitro, but its influence on pathogenicity remains unclear. In this study, we investigated the …

Brain infection by the fungus Cryptococcus neoformans results in inflammation of the
meninges and brain parenchyma, a condition known as meningoencephalitis. One million …