Colorectal cancer (CRC) arises from accumulated genetic and epigenetic alterations, which
provide the possibility to identify tumor-specific biomarkers by analyzing fecal DNA …

Background DNA methylation biomarkers in stool may have applications in early colorectal
cancer (CRC) detection; however, their association with stages of CRC carcinogenesis or …

AIM: To investigate the feasibility of detecting methylated fecal DNA as a screening tool for
colorectal carcinoma (CRC) and precancerous lesions. METHODS: Methylated secreted …

A large number of tumor-related methylated genes have been suggested to be of diagnostic
and prognostic values for CRC when analyzed in patients' stool samples; however, reported …

Objective To summarize the current evidence on the biomarkers associated with DNA
methylation in the screening and diagnosis of colorectal cancer (CRC). Methods A literature …

Background: An increasing number of hypermethylated genes in stool samples have been
reported as biomarkers for the detection of colorectal cancer (CRC) or adenomas. We aimed …

Since genetic and epigenetic alterations influence the development of colorectal cancer
(CRC), huge potential lies in the use of DNA methylation as biomarkers to improve the …

Detection of colorectal cancer at an early stage may significantly decrease mortality from the
disease. The current screening test of colonoscopy is of high efficacy, but its acceptance in …

DNA methylation biomarkers for noninvasive diagnosis of colorectal cancer (CRC) and
precursor lesions have been extensively studied. Different panels have been reported …

Aberrant DNA methylation is frequently detected in gastrointestinal tumors, and can
therefore potentially be used to screen, diagnose, prognosticate, and predict colorectal …