Environmental chemicals differentially affect epigenetic-related mechanisms in the zebrafish liver (ZF-L) cell line and in zebrafish embryos

M Blanc, J Rüegg, N Scherbak, SH Keiter - Aquatic toxicology, 2019 - Elsevier
A number of chemicals have been shown to affect epigenetic patterning and functions. Since
epigenetic mechanisms regulate transcriptional networks, epigenetic changes induced by …

[HTML][HTML] Epigenetic transgenerational modifications induced by xenobiotic exposure in zebrafish

L Terrazas-Salgado, A García-Gasca… - Frontiers in Cell and …, 2022 - frontiersin.org
Zebrafish (Danio rerio) is a well-established vertebrate model in ecotoxicology research that
responds to a wide range of xenobiotics such as pesticides, drugs, and endocrine-disrupting …

Role of DNA methylation in altered gene expression patterns in adult zebrafish (Danio rerio) exposed to 3, 3', 4, 4', 5-pentachlorobiphenyl (PCB 126)

N Aluru, SI Karchner, KS Krick, W Zhu… - Environmental …, 2018 - academic.oup.com
There is growing evidence that environmental toxicants can affect various physiological
processes by altering DNA methylation patterns. However, very little is known about the …

Epigenetic effects of environmental chemicals: insights from zebrafish

N Aluru - Current opinion in toxicology, 2017 - Elsevier
Zebrafish have been extensively used for studying vertebrate development and modeling
human diseases such as cancer. In the last two decades, they have also emerged as an …

Zebrafish as a model to study the role of DNA methylation in environmental toxicology

JH Kamstra, P Aleström, JM Kooter, J Legler - Environmental Science and …, 2015 - Springer
Environmental epigenetics is a rapidly growing field which studies the effects of
environmental factors such as nutrition, stress, and exposure to compounds on epigenetic …

Zebrafish embryos as a screen for DNA methylation modifications after compound exposure

MC Bouwmeester, S Ruiter, T Lommelaars… - Toxicology and applied …, 2016 - Elsevier
Modified epigenetic programming early in life is proposed to underlie the development of an
adverse adult phenotype, known as the Developmental Origins of Health and Disease …

Environmental epigenetics in zebrafish

V Cavalieri, G Spinelli - Epigenetics & chromatin, 2017 - Springer
It is widely accepted that the epigenome can act as the link between environmental cues,
both external and internal, to the organism and phenotype by converting the environmental …

Impacts of TCDD and MeHg on DNA methylation in zebrafish (Danio rerio) across two generations

PA Olsvik, TD Williams, H Tung, L Mirbahai… - … and Physiology Part C …, 2014 - Elsevier
This study aimed to investigate whether dioxin (TCDD) and methylmercury (MeHg) pose a
threat to offspring of fish exposed to elevated concentrations of these chemicals via …

The toxicological application of transcriptomics and epigenomics in zebrafish and other teleosts

TD Williams, L Mirbahai… - Briefings in functional …, 2014 - academic.oup.com
Zebrafish (Danio rerio) is one of a number of teleost fish species frequently employed in
toxicology. Toxico-genomics determines global transcriptomic responses to chemical …

Epigenetic biomarkers as tools for chemical hazard assessment: Gene expression profiling using the model Danio rerio

T Torres, R Ruivo, MM Santos - Science of The Total Environment, 2021 - Elsevier
Recent reports raise the concern that exposure to several environmental chemicals may
induce persistent changes that go beyond the exposed organisms, being transferred to …