[HTML][HTML] A genome-wide study of DNA methylation patterns and gene expression levels in multiple human and chimpanzee tissues
The modification of DNA by methylation is an important epigenetic mechanism that affects
the spatial and temporal regulation of gene expression. Methylation patterns have been …
the spatial and temporal regulation of gene expression. Methylation patterns have been …
[PDF][PDF] Divergent whole-genome methylation maps of human and chimpanzee brains reveal epigenetic basis of human regulatory evolution
DNA methylation is a pervasive epigenetic DNA modification that strongly affects chromatin
regulation and gene expression. To date, it remains largely unknown how patterns of DNA …
regulation and gene expression. To date, it remains largely unknown how patterns of DNA …
[PDF][PDF] Differences in DNA methylation patterns between humans and chimpanzees
Methylation at CpG dinucleotides is important for gene regulation in mammals [1]. However,
it is unknown how methylation patterns change during evolution. Here, we compare …
it is unknown how methylation patterns change during evolution. Here, we compare …
[HTML][HTML] Dynamics of DNA methylation in recent human and great ape evolution
I Hernando-Herraez, J Prado-Martinez, P Garg… - PLoS …, 2013 - journals.plos.org
DNA methylation is an epigenetic modification involved in regulatory processes such as cell
differentiation during development, X-chromosome inactivation, genomic imprinting and …
differentiation during development, X-chromosome inactivation, genomic imprinting and …
[HTML][HTML] Tissue-specific DNA methylation is conserved across human, mouse, and rat, and driven by primary sequence conservation
Background Uncovering mechanisms of epigenome evolution is an essential step towards
understanding the evolution of different cellular phenotypes. While studies have confirmed …
understanding the evolution of different cellular phenotypes. While studies have confirmed …
A comparison of gene expression and DNA methylation patterns across tissues and species
Previously published comparative functional genomic data sets from primates using frozen
tissue samples, including many data sets from our own group, were often collected and …
tissue samples, including many data sets from our own group, were often collected and …
DNA methylation contributes to natural human variation
DNA methylation patterns are important for establishing cell, tissue, and organism
phenotypes, but little is known about their contribution to natural human variation. To …
phenotypes, but little is known about their contribution to natural human variation. To …
DNA methylation profile of tissue-dependent and differentially methylated regions (T-DMRs) in mouse promoter regions demonstrating tissue-specific gene expression
S Yagi, K Hirabayashi, S Sato, W Li… - Genome …, 2008 - genome.cshlp.org
DNA methylation constitutes an important epigenetic regulation mechanism in many
eukaryotes, although the extent of DNA methylation in the regulation of gene expression in …
eukaryotes, although the extent of DNA methylation in the regulation of gene expression in …
DNA methylation-based variation between human populations
F Kader, M Ghai - Molecular genetics and genomics, 2017 - Springer
Several studies have proved that DNA methylation affects regulation of gene expression and
development. Epigenome-wide studies have reported variation in methylation patterns …
development. Epigenome-wide studies have reported variation in methylation patterns …
Epigenetics: differential DNA methylation in mammalian somatic tissues
H Nagase, S Ghosh - The FEBS journal, 2008 - Wiley Online Library
Epigenetics refers to heritable phenotypic alterations in the absence of DNA sequence
changes, and DNA methylation is one of the extensively studied epigenetic alterations. DNA …
changes, and DNA methylation is one of the extensively studied epigenetic alterations. DNA …