Methylation of genomes and genes at the invertebrate-vertebrate boundary

S Tweedie, J Charlton, V Clark… - Molecular and cellular …, 1997 - Taylor & Francis
Patterns of DNA methylation in animal genomes are known to vary from an apparent
absence of modified bases, via methylation of a minor fraction of the genome, to genome …

Ecological epigenetics in marine metazoans

GE Hofmann - Frontiers in Marine Science, 2017 - frontiersin.org
In this horizon scan article, I review the emerging area of ecological epigenetics in marine
animals with studies of DNA methylation as the primary focus. Epigenetic mechanisms such …

A context dependent role for DNA methylation in bivalves

MR Gavery, SB Roberts - Briefings in functional genomics, 2014 - academic.oup.com
The function of DNA methylation in species such as bivalves where the limited amount of
DNA methylation is predominantly found in gene bodies remains unclear. An emerging …

Whole-mount MeFISH: a novel technique for simultaneous visualization of specific DNA methylation and protein/RNA expression

H Shiura, A Okamoto, H Sasaki, K Abe - PloS one, 2014 - journals.plos.org
To understand the spatiotemporal changes in cellular status that occur during embryonic
development, it is desirable to detect simultaneously the expression of genes, proteins, and …

Genome-Wide Analysis of DNA Methylation in Five Tissues of Zhikong Scallop, Chlamys farreri

Y Sun, R Hou, X Fu, C Sun, S Wang, C Wang, N Li… - PloS one, 2014 - journals.plos.org
DNA methylation plays a vital role in tissue development and differentiation in eukaryotes.
Epigenetic studies have been seldom conducted in the extremely diverse and evolutionarily …

Strand-specific single-cell methylomics reveals distinct modes of DNA demethylation dynamics during early mammalian development

M Sen, D Mooijman, A Chialastri, JC Boisset… - Nature …, 2021 - nature.com
DNA methylation (5mC) is central to cellular identity. The global erasure of 5mC from the
parental genomes during preimplantation mammalian development is critical to reset the …

DNA methylation, epigenetics, and evolution in vertebrates: facts and challenges

A Varriale - International journal of evolutionary biology, 2014 - Wiley Online Library
DNA methylation is a key epigenetic modification in the vertebrate genomes known to be
involved in biological processes such as regulation of gene expression, DNA structure and …

Computational approaches for understanding the evolution of DNA methylation in animals

SV Yi, MAD Goodisman - Epigenetics, 2009 - Taylor & Francis
DNA methylation is implicated in modulating gene transcription in a wide array of taxa.
However, a complete understanding of the specific function of DNA methylation requires …

Conservation and divergence in eukaryotic DNA methylation

T Lee, J Zhai, BC Meyers - Proceedings of the National …, 2010 - National Acad Sciences
Cytosine methylation is a com-mon DNA modification found in most eukaryotic organisms
including plants, animals, and fungi (1, 2). The addition of a methyl group to cytosine …

DNA methylation is maintained with high fidelity in the honey bee germline and exhibits global non-functional fluctuations during somatic development

KD Harris, JPB Lloyd, K Domb, D Zilberman… - Epigenetics & …, 2019 - Springer
Background DNA methylation of active genes, also known as gene body methylation, is
found in many animal and plant genomes. Despite this, the transcriptional and …