Deciphering a methylome: what can we read into patterns of DNA methylation?

KB Flores, GV Amdam - Journal of Experimental Biology, 2011 - journals.biologists.com
The methylation of cytosines within cytosine–guanine (CG) dinucleotides is an epigenetic
mark that can modify gene transcription. With the advent of high-throughput sequencing, it is …

DNA methylation dynamics in the germline of the marsupial tammar wallaby, Macropus eugenii

T Ishihara, D Hickford, G Shaw, AJ Pask… - DNA …, 2019 - academic.oup.com
Parent specific-DNA methylation is the genomic imprint that induces mono-allelic gene
expression dependent on parental origin. Resetting of DNA methylation in the germ line is …

Evolution of DNA methylome diversity in eukaryotes

A de Mendoza, R Lister, O Bogdanovic - Journal of Molecular Biology, 2020 - Elsevier
Cytosine DNA methylation (5mC) is a widespread base modification in eukaryotic genomes
with critical roles in transcriptional regulation. In recent years, our understanding of 5mC has …

Absence of global genomic cytosine methylation pattern erasure during medaka (Oryzias latipes) early embryo development

RB Walter, HY Li, GW Intano, S Kazianis… - … and Physiology Part B …, 2002 - Elsevier
Two techniques were used to analyze global genomic 5-methyl cytosine methylation at
CCGG sites of medaka embryo DNA. DNA was labeled by incorporation of microinjected …

Genome-wide analysis in the mouse embryo reveals the importance of DNA methylation for transcription integrity

T Dahlet, A Argüeso Lleida, H Al Adhami… - Nature …, 2020 - nature.com
Mouse embryos acquire global DNA methylation of their genome during implantation.
However the exact roles of DNA methyltransferases (DNMTs) in embryos have not been …

Genome‐wide DNA methylation patterns harbour signatures of hatchling sex and past incubation temperature in a species with environmental sex determination

SL Bock, CR Smaga, JA McCoy… - Molecular Ecology, 2022 - Wiley Online Library
Conservation of thermally sensitive species depends on monitoring organismal and
population‐level responses to environmental change in real time. Epigenetic processes are …

[HTML][HTML] Predominant intragenic methylation is associated with gene expression characteristics in a bivalve mollusc

MR Gavery, SB Roberts - PeerJ, 2013 - peerj.com
Abstract Characterization of DNA methylation patterns in the Pacific oyster, Crassostrea
gigas, indicates that this epigenetic mechanism plays an important functional role in gene …

[HTML][HTML] Beyond DNA: programming and inheritance of parental methylomes

JA Hackett, MA Surani - Cell, 2013 - cell.com
Epigenetic reprogramming of parental genomes following fertilization is important to ensure
compatibility for totipotency and development thereafter. New studies by Jiang et al. and …

Zebrafish preserve global germline DNA methylation while sex-linked rDNA is amplified and demethylated during feminisation

O Ortega-Recalde, RC Day, NJ Gemmell… - Nature …, 2019 - nature.com
The germline is the only cellular lineage capable of transferring genetic information from one
generation to the next. Intergenerational transmission of epigenetic memory through the …

Developmental remodelling of non-CG methylation at satellite DNA repeats

SE Ross, A Angeloni, FS Geng… - Nucleic Acids …, 2020 - academic.oup.com
In vertebrates, DNA methylation predominantly occurs at CG dinucleotides however,
widespread non-CG methylation (mCH) has been reported in mammalian embryonic stem …