[HTML][HTML] Distinct human papillomavirus type 16 methylomes in cervical cells at different stages of premalignancy

JL Brandsma, Y Sun, PM Lizardi, DP Tuck, D Zelterman… - Virology, 2009 - Elsevier
Human papillomavirus (HPV) gene expression is dramatically altered during cervical
carcinogenesis. Because dysregulated genes frequently show abnormal patterns of DNA …

Patterns of cellular and HPV 16 methylation as biomarkers for cervical neoplasia

DA Patel, LS Rozek, JA Colacino… - Journal of virological …, 2012 - Elsevier
Aberrant promoter methylation of biologically relevant genes in cervical cancer and uneven
CpG distribution within the human papillomavirus 16 (HPV 16) enhancer region have been …

Methylation of viral and host genes and severity of cervical lesions associated with human papillomavirus type 16

K Louvanto, EL Franco… - … journal of cancer, 2015 - Wiley Online Library
Methylation of human papillomavirus (HPV) and host genes may predict cervical cancer risk.
We examined the methylation status of selected sites in HPV16 and human genes in DNA …

Conserved methylation patterns of human papillomavirus type 16 DNA in asymptomatic infection and cervical neoplasia

M Kalantari, IE Calleja-Macias, D Tewari… - Journal of …, 2004 - Am Soc Microbiol
ABSTRACT DNA methylation contributes to the chromatin conformation that represses
transcription of human papillomavirus type16 (HPV-16), which is prevalent in the etiology of …

Methylation status of the long control region of HPV 16 in clinical cervical specimens

D Hong, F Ye, W Lu, Y Hu, X Wan… - Molecular …, 2008 - spandidos-publications.com
DNA methylation is one of the regulatory pathways that modulate human papillomavirus
(HPV) gene expression. To obtain detailed methylation information on crucial areas of the …

Methylation of human papillomavirus-52 and-58 is a candidate biomarker in cervical neoplasia

I Murakami, T Fujii, K Dan, M Saito, A Ohno… - Journal of Clinical …, 2013 - Elsevier
Background Previous studies of human papillomavirus (HPV) 16/18 genome methylation
have concluded that methylation status of the L1 gene might act as a biomarker for cervical …

Quantitative measurement of Human Papillomavirus type 16 L1/L2 DNA methylation correlates with cervical disease grade

D Bryant, A Tristram, T Liloglou, S Hibbitts… - Journal of Clinical …, 2014 - Elsevier
Abstract Background Persistent infection with Human Papillomavirus (HPV) type 16 causes
the majority of cervical cancers. Genital HPV infection is very common, but neoplastic …

[HTML][HTML] Genotype-specific methylation of HPV in cervical intraepithelial neoplasia

YW Hsu, RL Huang, PH Su, YC Chen… - Journal of …, 2017 - ncbi.nlm.nih.gov
Objective Hypermethylation of human papillomavirus (HPV) and host genes has been
reported in cervical cancer. However, the degree of methylation of different HPV types …

[HTML][HTML] HPV DNA methylation at the early promoter and E1/E2 integrity: A comparison between HPV16, HPV18 and HPV45 in cervical cancer

SM Amaro-Filho, CBP Chaves, SP Felix, DL Basto… - Papillomavirus …, 2018 - Elsevier
Objectives To compare and describe type-specific characteristics of HPV16, HPV18 and
HPV45 in cervical cancer with respect to 3′ LCR methylation and disruption of E1/E2 …

Methylation of HPV18, HPV31, and HPV45 genomes and cervical intraepithelial neoplasia grade 3

N Wentzensen, C Sun, A Ghosh… - Journal of the …, 2012 - academic.oup.com
Background Persistent infections with carcinogenic human papillomavirus (HPV) types are
the necessary cause of cervical cancer. We recently demonstrated that the HPV16 genome …