Since the creation of the first transgenic animals four decades ago, a wide ethical consensus
has been reached that in contrast to a somatic gene therapy, germline gene interventions in …

The current kerfuffle around the use of CRISPR/Cas9 and other gene editing technologies in
human germline research is the latest in a series of related controversies at the intersection …

Recent studies using gene editing tools such as CRISPR/Cas9 have shown an enormously
broad spectrum of possible future applications. This genetic engineering technique allows …

With recent reports that a Chinese scientist used CRISPR-Cas9 to heritably edit the
genomes of human embryos (ie, germline editing) brought to term, discussions regarding …

Genome editing based on site-directed nucleases facilitated efficient and versatile genetic
modifications in human cells. However, recent reports, demonstrating CRISPR/Cas9 …

Although germline editing has been the subject of debate ever since the 1980s, it tended to
be based rather on speculative assumptions until April 2015, when CRISPR/Cas9 …

Europe is resolutely on its way to reaffirming a 20-year-old policy banning all inheritable
interventions involving the human genome. This approach, which was well justified two …

The mere idea of altering the human germ line has caused excitement as well as fears since
decades. The good and, in particular, the dubious motives for such interventions and the …

For the longest time, categorical objections against modifying human embryos for the
purpose of reproduction have played a dominant role in bioethics. Such interventions were …

Genome editing allows for the versatile genetic modification of somatic cells, germ cells and
embryos. In particular, CRISPR/Cas9 is worldwide used in biomedical research. Although …