Here, we summarize current knowledge about epigenetic reprogramming during
mammalian preimplantation development, as well as the potential mechanisms driving …

Epigenetic reprogramming in early preimplantation embryos, that refers to erasing and
remodeling epigenetic marks such as DNA methylation, is essential for differentiation and …

Vertebrate genomes are marked by notably high levels of 5-cytosine DNA methylation
(5meC). The clearest function of DNA methylation among members of the subphylum is …

Virtually all mammalian species including mouse, rat, pig, cow, and human, but not sheep
and rabbit, undergo genome‐wide epigenetic reprogramming by demethylation of the male …

In mouse and most other mammalian species, the paternal and maternal genomes undergo
parent-specific epigenetic reprogramming during preimplantation development. The …

DNA methylation is essential for the control of a number of biological mechanisms in
mammals [1]. Mammalian development is accompanied by two major waves of genome …

Methylation of DNA is an essential epigenetic control mechanism in mammals. During
embryonic development, cells are directed toward their future lineages, and DNA …

Dynamic epigenetic modification of the genome occurs during early development of the
mouse. Active demethylation of the paternal genome occurs in the zygote, followed by …

Background In mammals the parental genomes are epigenetically reprogrammed after
fertilization. This reprogramming includes a rapid demethylation of the paternal (sperm …

In this review, advances in the understanding of epigenetic reprogramming from fertilization
to the development of primordial germline cells in a mouse and human embryo are …