DNA methylation is an essential epigenetic mechanism involved in many essential cellular
processes. During development epigenetic reprograming takes place during gametogenesis …

DNA methylation is a carrier of important regulatory information that undergoes global
reprogramming in the mammalian germ line, including pre-implantation embryos and …

Landmark features of imprinted genes are differentially methylated domains (DMDs), in
which one parental allele is methylated on CpG dinucleotides and the opposite allele is …

DNA methylation plays essential roles in mammals. Of particular interest are parental
methylation marks that originate from the oocyte or the sperm, and bring about mono-allelic …

DNA methylation is an essential epigenetic mark crucial for normal mammalian
development. This modification controls the expression of a unique class of genes …

Thousands of regions in gametes have opposing methylation profiles that are largely
resolved during the post-fertilization epigenetic reprogramming. However some specific …

Background Genes subject to genomic imprinting are mono-allelically expressed in a parent-
of-origin dependent manner. Each imprinted locus has at least one differentially methylated …

Epigenetic modifications established during gametogenesis regulate transcription and other
nuclear processes in gametes, but also have influences in the zygote, embryo and postnatal …

DNA methylation is an important epigenetic modification that undergoes dynamic changes
in mammalian embryogenesis, during which both parental genomes are reprogrammed …

Mammalian imprinted genes are associated with differentially methylated regions (DMRs)
that are CpG methylated on one of the two parental chromosomes. In mice, at least 21 DMRs …