The pathogenic fungus, Cryptococcus neoformans, is known to undergo phenotypic
variation, which affects its virulence in the host. Recent investigations on C. neoformans …

Cryptococcus neoformans, similar to other eukaryotes, undergoes replicative aging.
Replicative life spans have been determined for clinical C. neoformans strains, and although …

Does cell age matter in virulence? The emergence of persister cells during chronic
infections is critical for persistence of infection, but little is known how this occurs. Here, we …

Although several virulence factors and associated genes have been identified, the
mechanisms that allow Cryptococcus neoformans to adapt during chronic infection and to …

While a myriad of studies have examined host factors that predispose persons to infection
with the opportunistic fungal pathogen Cryptococcus neoformans, comparatively little has …

The fungus Cryptococcus neoformans is pervasive in our environment and causes the
infectious disease cryptococcosis in humans, most commonly in immunocompromised …

Cryptococcus neoformans is an opportunistic fungal pathogen that causes life-threatening
meningitis primarily in immunocompromised individuals. In order to survive and proliferate …

Cryptococcus neoformans is a common life-threatening human fungal pathogen. The size of
cryptococcal cells is typically 5 to 10 µm. Cell enlargement was observed in vivo, producing …

Cryptococcus neoformans is a fungal pathogen with worldwide distribution. Serological
studies of human populations show a high prevalence of human infection, which rarely …

Cryptococcus neoformans is a facultative intracellular fungal pathogen. Ten-generation-old
(10GEN) C. neoformans cells are more resistant to phagocytosis and killing by …