The diagnosis, treatment and prevention of high altitude cerebral edema (HACE) are fairly
well established. The major unresolved issues are 1) the pathophysiology, 2) the individual …

We tested the hypothesis that dynamic cerebral autoregulation (CA) and blood–brain barrier
(BBB) function would be compromised in acute mountain sickness (AMS) subsequent to a …

Changes in cerebral blood flow (CBF) and regulation of cerebral circulation occur at high
altitude (HA). However, the changes in CBF and their associations with neurological …

This study was conducted to investigate whether the changes in the pulmonary diffusing
capacity found in individuals with acute mountain sickness (AMS) reflect the early stage of …

Traditionally, scientists and clinicians have explored peripheral physiological responses to
acute hypoxia to explain the pathophysiological processes that lead to acute mountain …

Hypoxia is implicated in aging and neurodegenerative diseases. We posited that changes in
gene expression induced by ambient hypoxia at altitude may be neuroprotective to natives …

Purpose Neurological impairment, mental dysfunction, and brain imaging changes caused
by severe hypoxia have been described by several authors. However, the occurrence of …

Acute mountain sickness (AMS) and high-altitude cerebral edema (HACE) are essentially
neurological disorders. The five symptoms included in the Lake Louise AMS symptom score …

We observed patients with chronic mountain sickness (CMS) in our clinic who developed
progressive neurological deterioration (encephalopathy) and we wished to investigate this …

As high altitude travel increases, acute mountain sickness (AMS) and life threatening high
altitude cerebral oedema (HACE) are becoming more prevalent. Acute mountain sickness …