Purpose Speech and language disorders are hallmark features of 22q11. 2 deletion
syndrome (22qDS). Learning disabilities, cognitive deficits, palate abnormalities …

Background Speech problems are a common clinical feature of the 22q11. 2 deletion
syndrome. The objectives of this study were to inventory the speech history and current self …

Palatal involvement occurs commonly in patients with 22q11. 2 Deletion Syndrome (22qDS),
and includes palatal clefting and velopharyngeal dysfunction in the absence of overt or …

Background Velopharyngeal insufficiency is an uncommon complication of adenoidectomy.
Persistent velopharyngeal insufficiency following adenoidectomy (VIA) may occur in …

Objective: To determine the efficacy and resource utilization of through-and-through
dissection of the soft palate for pharyngeal flap inset for velopharyngeal incompetence (VPI) …

Background The 22q11. 2 chromosome deletion syndrome occurs at a frequency of 1 in
4000 live births. Fluorescent in situ hybridization is a reliable means of testing for this …

Objective 22q11. 2 deletion syndrome is the most common genetic cause of velopharyngeal
dysfunction (VPD). Magnetic resonance imaging (MRI) is a promising method for …

The allelic loss of 22q11. 2 results in various developmental failures of pharyngeal pouch
derivatives (“22q11. 2 deletion syndromes”, 22q. 11DS), consequently affecting the anatomy …

Abstract 22q11. 2 microdeletion syndrome (22q11. 2DS) is the most common syndrome
associated with cleft palate and velopharyngeal insufficiency (VPI). Over 180 clinical …

The 22q11. 2 deletion syndrome represents a contiguous gene syndrome with a highly
variable phenotype. To date, over 180 clinical features have been described. Studies have …