Amentoflavone inhibits hepatocellular carcinoma progression through blockage of ERK/NF-ĸB activation
KC Lee, WT Chen, YC Liu, SS Lin, FT Hsu - in vivo, 2018 - iv.iiarjournals.org
Aim: The aim of the present study was to confirm therapeutic efficacy and find probable
mechanism of action of amentoflavone in hepatocellular carcinoma (HCC) in vivo. Materials …
mechanism of action of amentoflavone in hepatocellular carcinoma (HCC) in vivo. Materials …
Amentoflavone inhibits ERK-modulated tumor progression in hepatocellular carcinoma in vitro
Background/Aim: A previous study indicated that amentoflavone inhibits tumor growth of
breast cancer. However, the anti-cancer effects and mechanism of amentoflavone in …
breast cancer. However, the anti-cancer effects and mechanism of amentoflavone in …
Amentoflavone enhances the therapeutic efficacy of sorafenib by inhibiting anti-apoptotic potential and potentiating apoptosis in hepatocellular carcinoma in vivo
JJ Tsai, FT Hsu, PJ Pan, CW Chen… - Anticancer research, 2018 - ar.iiarjournals.org
Background/Aim: In a previous study, we showed that amentoflavone promotes sorafenib-
induced apoptosis in hepatocellular carcinoma (HCC) cells in vitro. However, whether …
induced apoptosis in hepatocellular carcinoma (HCC) cells in vitro. However, whether …
Amentoflavone reverses epithelial‐mesenchymal transition in hepatocellular carcinoma cells by targeting p53 signalling pathway axis
HY Jian, JT Zhang, Z Liu, Z Zhang… - Journal of Cellular and …, 2024 - Wiley Online Library
Epithelial‐mesenchymal transition (EMT) and its reversal process are important potential
mechanisms in the development of HCC. Selaginella doederleinii Hieron is widely used in …
mechanisms in the development of HCC. Selaginella doederleinii Hieron is widely used in …
Inactivation of AKT/ERK signaling and induction of apoptosis are associated with amentoflavone sensitization of hepatocellular carcinoma to lenvatinib
CJ Yang, MH Wu, JJ Tsai, FT Hsu, TC Hsia… - Anticancer …, 2022 - ar.iiarjournals.org
Background/Aim: AKT/ERK signaling transduction and anti-apoptosis effects have both been
recognized as important mediators of hepatocellular carcinoma (HCC) progression …
recognized as important mediators of hepatocellular carcinoma (HCC) progression …
Amentoflavone induces cell-cycle arrest, apoptosis, and invasion inhibition in non-small cell lung cancer cells
WT Chen, CH Chen, HT Su, PF Yueh, FT Hsu… - Anticancer …, 2021 - ar.iiarjournals.org
Background/Aim: Amentoflavone, an effective compound derived from medicinal plants, has
been shown to boost therapeutic efficacy of chemotherapy in non-small cell lung cancer …
been shown to boost therapeutic efficacy of chemotherapy in non-small cell lung cancer …
Amentoflavone enhances sorafenib-induced apoptosis through extrinsic and intrinsic pathways in sorafenib-resistant hepatocellular carcinoma SK-Hep1 cells in vitro
WL Chen, CL Hsieh, JH Chen… - Oncology …, 2017 - spandidos-publications.com
The present study aimed to evaluate the effects of amentoflavone on sorafenib-induced
apoptosis in sorafenib-resistant hepatocellular carcinoma (HCC) cells. The sorafenib …
apoptosis in sorafenib-resistant hepatocellular carcinoma (HCC) cells. The sorafenib …
Amentoflavone Effectively Blocked the Tumor Progression of Glioblastoma via Suppression of ERK/NF-B Signaling Pathway
FT Hsu, IT Chiang, YC Kuo, TC Hsia… - The American journal …, 2019 - World Scientific
Glioblastoma is the most common primary malignant tumor of the central nervous system,
with an annual incidence of 5.26 per 100000 people. The clinical outcome of standard …
with an annual incidence of 5.26 per 100000 people. The clinical outcome of standard …
Suppression of ERK/NF-κB activation is associated with amentoflavone-inhibited osteosarcoma progression in vivo
YJ Lee, JG Chung, YT Chien, SS Lin… - Anticancer research, 2019 - ar.iiarjournals.org
Background/Aim: Amentoflavone has been implicated in reducing the metastatic potential of
osteosarcoma (OS) cells in vitro. The aim of the present study was to verify the antitumoral …
osteosarcoma (OS) cells in vitro. The aim of the present study was to verify the antitumoral …
Amentoflavone induces anti-angiogenic and anti-metastatic effects through suppression of NF-κB activation in MCF-7 cells
JH Chen, WL Chen, YC Liu - Anticancer Research, 2015 - ar.iiarjournals.org
The aim of the present study was to investigate whether amentoflavone induces anti-
angiogenic and anti-metastatic effects through suppression of NF-κB activation in breast …
angiogenic and anti-metastatic effects through suppression of NF-κB activation in breast …