Angiotensin II (AngII) infusion initiates abdominal aortic aneurysm (AAA) development due
to medial disruption and results in luminal dilation and thrombus formation. The objective of …

Objective—We sought to define the temporal characteristics of angiotensin II (AngII)-induced
abdominal aortic aneurysms (AAAs) and to provide mechanistic insight into the development …

AngII (angiotensin II) infusion in mice has been used to provide mechanistic insight into
human abdominal aortic aneurysms for over 2 decades. This is a technically facile animal …

An abdominal aortic aneurysm (AAA) is an enlargement of the greatest artery in the body
defined as an increase in diameter of 1.5-fold. AAAs are common in the elderly population …

Objective—Abdominal aortic aneurysm (AAA) is widespread among elderly people and
results in progressive expansion and rupture of the aorta with high mortality. Macrophages …

The mediators for the initiation, progression, and rupture of abdominal aortic aneurysms
(AAAs) have not been defined. Recent evidence has demonstrated that chronic infusion of …

Objective—The presence of apoptotic markers is a prominent histological feature of
abdominal aortic aneurysm. To understand the role of apoptosis in the pathogenesis of this …

Abdominal aortic aneurysms (AAA) have a high prevalence in aged populations and are
responsible for a large number of deaths. Despite the widespread nature of the disease …

Increased plasma concentrations of angiotension II (Ang II) have been implicated in
atherogenesis. To examine this relationship directly, we infused Ang II or vehicle for 1 month …

Abstract Aims Angiotensin II-infused ApoE-/-mice are a popular mouse model for preclinical
aneurysm research. Here, we provide insight in the often-reported but seldom-explained …