OBJECTIVE: An ideal animal model of abdominal aortic aneurysm (AAA) is of great
importance for clarifying unknown complex mechanisms of the pathogenesis. We introduce …

Background The purpose of this study was to introduce a novel, simple and effective
technique for creating a reliable rabbit model of abdominal aortic aneurysm (AAA) via a …

OBJECTIVES: To modify the method for creating an abdominal aortic aneurysm in rabbits,
and to study its performance. MATERIALS AND METHODS: A total of 24 New Zealand white …

Background The perfused elastase AAA model and subcutaneous Angiotensin II infusion
AAA model are widely used murine AAA models. We modified these two current models and …

Purpose: Research investigating abdominal aortic aneurysms (AAAs) commonly uses a rat
model dependent on aortic infusion of porcine pancreatic elastase to initiate AAA formation …

Background: Many studies have been performed in order to model abdominal aortic
aneurysm (AAA) in an experimental animal, most commonly in small laboratory animals. In …

Objective The purpose of this study was to establish a reliable, chronic model of abdominal
aortic aneurysm (AAA). Methods Wild-type 8-week-old C56BL/6 male mice (n= 120) were …

Objective This study tested the hypothesis that an experimental model of abdominal aortic
aneurysm in rabbits results in progressive enlargement when induced by a combination of …

Animal models of abdominal aortic aneurysms (AAA) enable preclinical studies on new
therapeutic approaches and help to understand pathophysiology of the disease. The aim of …

Topical application of elastase to induce arterial aneurysm formation is an emerging murine
model of vascular disease. In the context of aortic abdominal aneurysm (AAA), angiotensin II …