Considering the widespread use of assisted reproductive techniques (ART), DNA
methylation of specific genes involved in spermatogenesis achieves increasingly clinical …

BACKGROUND Studies in non-human mammals suggest that environmental factors can
influence spermatozoal DNA methylation, and some research suggests that spermatozoal …

Infertility is a significant problem for human reproduction, with males and females equally
affected. However, the molecular mechanisms underlying male infertility remain unclear …

Sperm DNA methylation abnormalities have been detected in oligozoospermic men.
However, the association between sperm DNA methylation defects, sperm parameters and …

Abstract STUDY QUESTION Are there DNA methylation alterations in sperm that could
explain the reduced biological fertility of male partners from couples with unexplained …

OBJECTIVE: To evaluate genome-wide DNA methylation patterns in sperm from men with
abnormal sperm chromatin packaging and patients displaying abnormal embryogenesis …

OBJECTIVE: To evaluate the associations between proper protamine incorporation and
DNA methylation at imprinted loci. DESIGN: Experimental research study. SETTING …

Objective To evaluate the relationship between epigenetic patterns in sperm and fecundity.
Design Prospective study. Setting Academic andrology and in vitro fertilization laboratory …

Objective To evaluate whether male fertility status and/or embryo quality during in vitro
fertilization (IVF) therapy can be predicted based on genomewide sperm deoxyribonucleic …

In recent years, a number of studies focused on the role of epigenetics, including DNA
methylation, in spermatogenesis and male infertility. We aimed to provide an overview of the …