Epigenetic components drive the inheritance of transcriptional programs. This cellular
memory is crucial for the stable maintenance of cell fates throughout development …

Polycomb group (PcG) proteins are well-conserved chromatin factors that repress the
transcription of their target genes. They bind to the genome at specific sites and act on …

Polycomb group (PcG) proteins are transcriptional repressors that control expression of
developmental regulator genes in animals and plants. Recent advances in our …

The first genes composing the Polycomb group (PcG) were identified 50 years ago in
Drosophila melanogaster as essential developmental functions that regulate the correct …

Polycomb group proteins (PcGs) are involved in gene repression through chromatin
modifications and required for the maintenance of both embryonic and adult stem cells …

Polycomb group (PcG) proteins are epigenetic regulators of transcription that have key roles
in stem-cell identity, differentiation and disease. Mechanistically, they function within …

Polycomb group (PcG) complexes maintain epigenetically repressed states that need to be
reprogrammed when cells become committed to differentiation. In contrast to the previously …

Master regulatory genes require stable silencing by the polycomb group (PcG) to prevent
misexpression during differentiation and development. Some PcG proteins covalently modify …

Polycomb group (PcG) complexes are multiprotein assemblages that bind to chromatin and
establish chromatin states leading to epigenetic silencing,. PcG proteins regulate homeotic …

Although the core subunits of Polycomb group (PcG) complexes are well characterized, little
is known about the dynamics of these protein complexes during cellular differentiation. We …