Transcriptional repression mediated by the human polycomb-group protein EED involves histone deacetylation

J van der Vlag, AP Otte - Nature genetics, 1999 - nature.com
Polycomb-group (PcG) proteins form multimeric protein complexes, which are involved in
maintaining the transcriptional repressive state of genes over successive cell generations 1 …

[HTML][HTML] Canonical PRC1 controls sequence-independent propagation of Polycomb-mediated gene silencing

HF Moussa, D Bsteh, R Yelagandula, C Pribitzer… - Nature …, 2019 - nature.com
Polycomb group (PcG) proteins play critical roles in the epigenetic inheritance of cell fate.
The Polycomb Repressive Complexes PRC1 and PRC2 catalyse distinct chromatin …

Polycomb response elements and targeting of Polycomb group proteins in Drosophila

J Müller, JA Kassis - Current opinion in genetics & development, 2006 - Elsevier
Polycomb group (PcG) proteins are conserved regulatory proteins that repress transcription
of particular target genes in animals and plants. Studies over the past decade have …

Changes in the distributions and dynamics of polycomb repressive complexes during embryonic stem cell differentiation

X Ren, C Vincenz, TK Kerppola - Molecular and Cellular Biology, 2008 - Taylor & Francis
Polycomb group (PcG) transcription regulatory proteins maintain cell identity by sustained
repression of numerous genes. The differentiation of embryonic stem (ES) cells induces a …

Polycomb function during oogenesis is required for mouse embryonic development

E Posfai, R Kunzmann, V Brochard… - Genes & …, 2012 - genesdev.cshlp.org
In mammals, totipotent embryos are formed by fusion of highly differentiated gametes.
Acquisition of totipotency concurs with chromatin remodeling of parental genomes, changes …

[HTML][HTML] Propagation of silencing: recruitment and repression of naive chromatin in trans by Polycomb repressed chromatin

M Lavigne, NJ Francis, IFG King, RE Kingston - Molecular cell, 2004 - cell.com
The Polycomb group (PcG) proteins maintain stable and heritable repression of homeotic
genes. Typically, Polycomb response elements (PRE) that direct PcG repression are located …

[HTML][HTML] Epigenetic regulation by polycomb group complexes: focus on roles of CBX proteins

R Ma, Y Zhang, T Sun, B Cheng - Journal of Zhejiang University Science B, 2014 - Springer
Polycomb group (PcG) complexes are epigenetic regulatory complexes that conduct
transcriptional repression of target genes via modifying the chromatin. The two best …

Different polycomb group CBX family proteins associate with distinct regions of chromatin using nonhomologous protein sequences

C Vincenz, TK Kerppola - Proceedings of the National …, 2008 - National Acad Sciences
Polycomb group proteins are transcriptional repressors recruited to many developmental
control genes. The specificity of polycomb group protein targeting is incompletely …

Structural basis for specific binding of Polycomb chromodomain to histone H3 methylated at Lys 27

J Min, Y Zhang, RM Xu - Genes & development, 2003 - genesdev.cshlp.org
The chromodomain of Drosophila Polycomb protein is essential for maintaining the silencing
state of homeotic genes during development. Recent studies suggest that Polycomb …

[HTML][HTML] Variant PCGF1-PRC1 links PRC2 recruitment with differentiation-associated transcriptional inactivation at target genes

H Sugishita, T Kondo, S Ito, M Nakayama… - Nature …, 2021 - nature.com
Abstract Polycomb repressive complexes-1 and-2 (PRC1 and 2) silence developmental
genes in a spatiotemporal manner during embryogenesis. How Polycomb group (PcG) …