Transcriptional repression mediated by the human polycomb-group protein EED involves histone deacetylation
J van der Vlag, AP Otte - Nature genetics, 1999 - nature.com
Polycomb-group (PcG) proteins form multimeric protein complexes, which are involved in
maintaining the transcriptional repressive state of genes over successive cell generations 1 …
maintaining the transcriptional repressive state of genes over successive cell generations 1 …
[HTML][HTML] Canonical PRC1 controls sequence-independent propagation of Polycomb-mediated gene silencing
Polycomb group (PcG) proteins play critical roles in the epigenetic inheritance of cell fate.
The Polycomb Repressive Complexes PRC1 and PRC2 catalyse distinct chromatin …
The Polycomb Repressive Complexes PRC1 and PRC2 catalyse distinct chromatin …
Polycomb response elements and targeting of Polycomb group proteins in Drosophila
J Müller, JA Kassis - Current opinion in genetics & development, 2006 - Elsevier
Polycomb group (PcG) proteins are conserved regulatory proteins that repress transcription
of particular target genes in animals and plants. Studies over the past decade have …
of particular target genes in animals and plants. Studies over the past decade have …
Changes in the distributions and dynamics of polycomb repressive complexes during embryonic stem cell differentiation
X Ren, C Vincenz, TK Kerppola - Molecular and Cellular Biology, 2008 - Taylor & Francis
Polycomb group (PcG) transcription regulatory proteins maintain cell identity by sustained
repression of numerous genes. The differentiation of embryonic stem (ES) cells induces a …
repression of numerous genes. The differentiation of embryonic stem (ES) cells induces a …
Polycomb function during oogenesis is required for mouse embryonic development
E Posfai, R Kunzmann, V Brochard… - Genes & …, 2012 - genesdev.cshlp.org
In mammals, totipotent embryos are formed by fusion of highly differentiated gametes.
Acquisition of totipotency concurs with chromatin remodeling of parental genomes, changes …
Acquisition of totipotency concurs with chromatin remodeling of parental genomes, changes …
[HTML][HTML] Propagation of silencing: recruitment and repression of naive chromatin in trans by Polycomb repressed chromatin
M Lavigne, NJ Francis, IFG King, RE Kingston - Molecular cell, 2004 - cell.com
The Polycomb group (PcG) proteins maintain stable and heritable repression of homeotic
genes. Typically, Polycomb response elements (PRE) that direct PcG repression are located …
genes. Typically, Polycomb response elements (PRE) that direct PcG repression are located …
[HTML][HTML] Epigenetic regulation by polycomb group complexes: focus on roles of CBX proteins
R Ma, Y Zhang, T Sun, B Cheng - Journal of Zhejiang University Science B, 2014 - Springer
Polycomb group (PcG) complexes are epigenetic regulatory complexes that conduct
transcriptional repression of target genes via modifying the chromatin. The two best …
transcriptional repression of target genes via modifying the chromatin. The two best …
Different polycomb group CBX family proteins associate with distinct regions of chromatin using nonhomologous protein sequences
C Vincenz, TK Kerppola - Proceedings of the National …, 2008 - National Acad Sciences
Polycomb group proteins are transcriptional repressors recruited to many developmental
control genes. The specificity of polycomb group protein targeting is incompletely …
control genes. The specificity of polycomb group protein targeting is incompletely …
Structural basis for specific binding of Polycomb chromodomain to histone H3 methylated at Lys 27
The chromodomain of Drosophila Polycomb protein is essential for maintaining the silencing
state of homeotic genes during development. Recent studies suggest that Polycomb …
state of homeotic genes during development. Recent studies suggest that Polycomb …
[HTML][HTML] Variant PCGF1-PRC1 links PRC2 recruitment with differentiation-associated transcriptional inactivation at target genes
H Sugishita, T Kondo, S Ito, M Nakayama… - Nature …, 2021 - nature.com
Abstract Polycomb repressive complexes-1 and-2 (PRC1 and 2) silence developmental
genes in a spatiotemporal manner during embryogenesis. How Polycomb group (PcG) …
genes in a spatiotemporal manner during embryogenesis. How Polycomb group (PcG) …