DNA methylation: the nuts and bolts of repression

TB Miranda, PA Jones - Journal of cellular physiology, 2007 - Wiley Online Library
DNA methylation is an epigenetic modification which plays an important role in chromatin
organization and gene expression. DNA methylation can silence genes and repetitive …

Controlling DNA methylation: many roads to one modification

M Freitag, EU Selker - Current opinion in genetics & development, 2005 - Elsevier
Genetic, biochemical and cytological studies on DNA methylation in several eukaryotic
organisms have resulted in leaps of understanding in the past three years. Discoveries of …

Genomic patterns of DNA methylation: targets and function of an epigenetic mark

M Weber, D Schübeler - Current opinion in cell biology, 2007 - Elsevier
Methylation of cytosines can mediate epigenetic gene silencing and is the only known DNA
modification in eukaryotes. Recent efforts to map DNA methylation across mammalian …

DNA methylation and silencing of gene expression

J Newell-Price, AJL Clark, P King - Trends in Endocrinology & Metabolism, 2000 - cell.com
DNA methylation is associated with the silencing of gene expression. The predominant
mechanism involves the methylation of DNA and the subsequent recruitment of binding …

How does DNA methylation repress transcription?

SU Kass, D Pruss, AP Wolffe - Trends in Genetics, 1997 - cell.com
DNA methylation has an essential regulatory function in mammalian development, serving
to repress nontranscribed genes stably in differentiated adult somatic cells. Recent data …

DNA methylation‐mediated epigenetic control

A Rottach, H Leonhardt, F Spada - Journal of cellular …, 2009 - Wiley Online Library
During differentiation and development cells undergo dramatic morphological and functional
changes without any change in the DNA sequence. The underlying changes of gene …

DNA methylation in epigenetic control of gene expression

A Razin, B Kantor - Epigenetics and chromatin, 2005 - Springer
Over three decades ago DNA methylation had been suggested to play a role in the
regulation of gene expression. This chapter reviews the development of this field of research …

DNA methylation and gene expression

Z Siegfried, I Simon - Wiley Interdisciplinary Reviews: Systems …, 2010 - Wiley Online Library
Methylation of cytosines is the key epigenetic modification of DNA in eukaryotes and is
associated with a repressed chromatin state and inhibition of gene expression. The …

[HTML][HTML] DNA methylation: a molecular lock

Z Siegfried, H Cedar - Current Biology, 1997 - cell.com
DNA methylation: A molecular lock: Current Biology Skip to Main Content Advertisement Current
Biology This journal offers authors two options (open access or subscription) to publish research …

Non-canonical functions of the DNA methylome in gene regulation

JP Reddington, S Pennings, RR Meehan - Biochemical Journal, 2013 - portlandpress.com
Methylation of the cytosine base in DNA, DNA methylation, is an essential epigenetic mark
in mammals that contributes to the regulation of transcription. Several advances have been …