DNA methylation—a regulatory signal in eukaryotic gene expression

W Doerfler - Journal of General Virology, 1981 - microbiologyresearch.org
There are at least two systems in which inhibitory effects of DNA modification on DNA-
protein interactions have been unambiguously demonstrated.(i) At sequences specifically …

DNA methylation and its possible biological roles

A Razin, J Friedman - Progress in nucleic acid research and molecular …, 1981 - Elsevier
Publisher Summary The chapter discusses on the DNA methylation and its possible
biological roles. The pattern of DNA methylation is species-specific. In the DNA of some …

DNA methylation and gene expression

H Cedar - DNA methylation: biochemistry and biological …, 1984 - Springer
Understanding the mechanisms involved in the regulation of gene expression in eukaryotic
organisms is one of the major challenges facing the modern molecular biologist. Despite …

[图书][B] DNA methylation: molecular biology and biological significance

J Jost, H Saluz - 2013 - books.google.com
The occurrence of 5-methylcytosine in DNA was first described in 1948 by Hotchkiss (see
first chapter). Recognition of its possible physiologi cal role in eucaryotes was first …

Methylation of DNA in prokaryotes

M Noyer-Weidner, TA Trautner - DNA methylation: molecular biology and …, 1993 - Springer
A much wider variety of biological functions of postreplicative DNA methylation is observed
in prokaryotes than in eukaryotes. In eukaryotes DNA methylation is primarily a means of the …

DNA methylation: eukaryotic defense against the transcription of foreign genes?

W Doerfler - Microbial pathogenesis, 1992 - Elsevier
The DNA of eukaryotes contains a fifth nucleotide, 5-methyldeoxycytidine (5-mC), whose
concentration in DNA varies from a few per cent in mammalian DNA to more than 30% of all …

DNA methylation and gene activity

W Doerfler - Annual review of biochemistry, 1983 - annualreviews.org
DNA methylation and its functional significance, particularly in eukaryotic systems, have
become very active areas of research. Although the biochem istry of DNA methylation has …

DNA methylation and gene expression

A Razin, H Cedar - Microbiological reviews, 1991 - Am Soc Microbiol
A large body of evidence demonstrates that DNA methylation plays a role in gene regulation
in animal cells. Not only is there a correlation between gene transcription and …

[引用][C] The essentials of DNA methylation

A Bird - cell, 1992 - Elsevier
An obstacle to progress in understanding eukaryotic DNA methylation has been the lack of a
good genetic systemthe most favorable eukaryotes for genetic analysis (yeasts …

Effect of regional DNA methylation on gene expression.

I Keshet, J Yisraeli, H Cedar - Proceedings of the National …, 1985 - National Acad Sciences
The effect of DNA methylation on the transcriptional activity of the hamster adenine
phosphoribosyltransferase (aprt) and the herpes thymidine kinase (tk) genes has been …