Background The perfused elastase AAA model and subcutaneous Angiotensin II infusion
AAA model are widely used murine AAA models. We modified these two current models and …

Background To create a novel procedure that will decrease the mortality of experimental
animals in the intraarterial infusion of elastase abdominal aortic aneurysm (AAA) model …

Background. Intraarterial infusion of elastase has been used to create an experimental
model of aortic aneurysm in rats. Unfortunately, the utility of this model is limited by a high …

Objective. This study was performed to determine whether it would be possible to shorten
the elastase infusion time in the elastase-induced rat aneurysm model. Methods. The …

OBJECTIVE: An ideal animal model of abdominal aortic aneurysm (AAA) is of great
importance for clarifying unknown complex mechanisms of the pathogenesis. We introduce …

The intraluminal elastase perfusion model has been proved to be potentially effective in
producing abdominal aortic aneurysm in rodents, but it produced unpredictable results in …

Introduction Given the unknown biologic antecedents before aortic aneurysm rupture, the
purpose of this study was to establish a reproducible model of aortic aneurysm rupture …

Purpose: Research investigating abdominal aortic aneurysms (AAAs) commonly uses a rat
model dependent on aortic infusion of porcine pancreatic elastase to initiate AAA formation …

Establishing an animal model of abdominal aortic aneurysm (AAA) is the key to study the
pathogenesis and the pathophysiological features of AAAs. We investigated the effects of …

Background. The morphologic changes in the aorta during elastase infusion, which have not
previously been investigated, were examined in the rat abdominal aortic aneurysm model …