Acacetin (5, 7-dihydroxy-4′-methoxyflavone) is a flavone compound, some of which have
anti-cancerous effects. Vascular endothelial growth factor (VEGF) plays an important role in …

Angiogenesis is an effective target in cancer control. The antiangiogenic efficacy and
associated mechanisms of acacetin, a plant flavone, are poorly known. In the present study …

Apigenin is a nontoxic dietary flavonoid that has been shown to possess anti‐tumor
properties and therefore poses special interest for the development of a novel …

Abstract Theaflavin-3, 3'-digallate (TF3) is a black tea polyphenol produced from
polymerization and oxidization of the green tea ployphenols epicatechin gallate and (-) …

Flavonoids have been recently identified as a potential anticancer agent against various
human epithelial cancers. In this study, the elucidation of mechanisms underlying the …

Objective. Abdominal aortic aneurysm (AAA) development has been characterized by
increased expression of vascular endothelial growth factor (VEGF), which contributes to …

Morelloflavone, a biflavonoid extracted from Garcinia dulcis, has shown antioxidative,
antiviral, and anti-inflammatory properties. However, the function and the mechanism of this …

Abstract Acacetin (5, 7-dihydroxy-4'-methoxyflavone) is a flavonoid compound with
antimutagenic, antiplasmodial, antiperoxidant, anti-inflammatory and anticancer effects …

Although many anti‐VEGF agents are available for cancer treatment, side effects of these
agents limit their application for cancer treatment and prevention. Here we studied the …

Hypoxia-inducible factor 1 (HIF-1) plays a pivotal role in tumor adaptation to
microenvironmental hypoxia, and it also exerts important roles in angiogenesis and tumor …